Results 81 to 90 of about 2,063,201 (347)
BMC Bioinformatics, 2009 Background Restriction enzymes can produce easily definable segments from DNA sequences by using a variety of cut patterns. There are, however, no software tools that can aid in gene building -- that is, modifying wild-type DNA sequences to express the ...
Stafford Phillip +4 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
G3: Genes, Genomes, Genetics, 2018 Genetic linkage maps are essential for comparative genomics, high quality genome sequence assembly and fine scale quantitative trait locus (QTL) mapping.
Philine G. D. Feulner +4 more
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Restricted Lie algebras with semilinear 𝑝-mappings [PDF]
Proceedings of the American Mathematical Society, 1984 Restricted Lie algebras ( L , [ p ] ) (L,[p]) having the property that some power of the p p -mapping [ p ] [p] is semilinear are investigated.
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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549 VISUALIZATION OF HUMAN GLOBIN GENES BY RESTRICTION ENDONUCLEASE MAPPING: A NEW APPROACH TO THE PRENATAL DIAGNOSIS OF GLOBIN GENE DELETION [PDF]
, 1978 Stuart H. Orkin, David G. Nathan
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Near BPS skyrmions and restricted harmonic maps [PDF]
Journal of Geometry and Physics, 2015 Motivated by a class of near BPS Skyrme models introduced by Adam, S nchez-Guill n and Wereszczy ski, the following variant of the harmonic map problem is introduced: a map $ :(M,g)\rightarrow (N,h)$ between Riemannian manifolds is restricted harmonic (RH) if it locally extremizes $E_2$ on its $SDiff(M)$ orbit, where $SDiff(M)$ denotes the group of
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Mapping the Trypanosoma cruzi Genome: Analyses of Representative Cosmid Libraries
BioTechniques, 1996 In order to generate contiguous cosmid coverage of the genome of the protozoan parasite Trypanosoma cruzi for large-scale sequence analysis, a cosmid library of 36864 individual, primary clones was generated.
J. Hanke +6 more
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FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source