Results 91 to 100 of about 10,530 (307)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The Evolution of Digital Trade: Understanding Opportunities and Risks in a Globalized Economy
Future Human ImageAs a new manifestation of traditional trade in the era of the digital economy, digital trade relies on the cross-border flow of data and information, while promoting global economic and trade growth, enhancing consumer welfare, and creating a new form of
Ying Yu
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Limitation of property rights in the interest of environment protection
, 2014 Saskaroties divām Satversmē garantētām pamattiesībām, tiesībām uz labvēlīgu vidi un īpašuma tiesībām, vienai no tām ir jādod priekšroka. Darba mērķis ir noskaidrot šo pamattiesību mijiedarbību un samērīguma principa piemērošanu to ierobežošanas gadījumā.
Briede, Elza
core
CONSTITUTIONAL ASPECTS OF THE EXPROPRIATION COMPENSATION
Zbornik Pravnog Fakulteta Sveučilišta u Rijeci, 2015 Expropriation is an institute of Administrative Law by which the state intervenes in property rights of certain subjects and takes away or restricts those rights for its own benefit or for the benefit of other entities.
Mario Jelušić, Duška Šarin
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Voilation of Property Rights Due to Restriction of Construction: Discussions on Recent Developments
, 2017 Temel hak ve özgürlükler arasında yer alan mülkiyet hakkı, ancak kanun ile bireysel yarar ile kamu yararı arasındaki adil dengenin gözetilmesi koşuluyla sınırlanabilir.
Oruç, Murat
core
European Journal of Law and Public Administration, 2019 The article analyzes the constitutional and legal regulation of property relations in the Ukraine and European legislation. The author concludes that the absence of direct instruction on a social function of property in the former postsoviet countries can be explained by the conditions in which their constitutions were adopted and by the aims which ...
openaire +1 more source