Results 111 to 120 of about 10,530 (307)

Access over private property-public property interest vs private rights

open access: yes, 2003
The New Zealand Kellogg Rural Leaders Programme develops emerging agribusiness leaders to help shape the future of New Zealand agribusiness and rural affairs.
Luxton Nicola
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Law-economics Analysis for the Restriction of Intellectual

open access: yes, 2009
The restriction of Intellectual property rights, as an important principle and system in the Intellectual property law, has its own existence of the reasonable economic basis.
NING, Li-zhi
core   +1 more source

Factors influencing limited repository access in academic libraries

open access: yesBerkala Ilmu Perpustakaan dan Informasi
Introduction. Several academic libraries have implemented restrictions on repository access in recent years. This study explores the phenomenon of restricted access in academic libraries in managing their repositories. Method.
Araf Aliwijaya, Safirotu Khoir
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

MEASURES TO ENSURE PROCEEDINGS IN ADMINISTRATIVE OFFENSES THAT RESTRICT PROPERTY RIGHTS

open access: yesNaukovyy Visnyk Dnipropetrovs kogo Derzhavnogo Universytety Vnutrishnikh Sprav
In Ukraine, there are many administrative and legal tools for law enforcement, protection of citizens’ rights and interests, in which the special place is taken by measures of ensuring proceedings in cases of administrative offenses. Their application implements the termination of administrative misconduct, identification of the offender, drawing up a ...
Andriy SOBAKAR, Oksana MYSLYVA
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The position of parliament in state of emergency and state of war within constitutional system of the Republic Of Serbia [PDF]

open access: yesNBP: Nauka, bezbednost, policija, 2015
State of emergency is a specific form of state of emergency in which there is a state due to the occurrence of unexpected and difficult circumstances for the survival of the property and citizens.
Jovičić Jelena
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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