Results 101 to 110 of about 6,061,790 (368)

Effects of mutations in phage restriction sites during escape from restriction–modification [PDF]

open access: yesBiology Letters, 2017
Restriction–modification systems are widespread genetic elements that protect bacteria from bacteriophage infections by recognizing and cleaving heterologous DNA at short, well-defined sequences called restriction sites. Bioinformatic evidence shows that restriction sites are significantly underrepresented in bacteriophage genomes, presumably because ...
Maroš Pleška, Călin C. Guet
openaire   +3 more sources

Restriction site heteroplasmy in the mitochondrial DNA of Brycon opalinus (Cuvier, 1819) (Characiformes, Characidae, Bryconiae)

open access: yesBrazilian Journal of Medical and Biological Research, 2004
Homoplasmy is a feature usually found in the mtDNA of higher animal taxa. On the other hand, the presence of two classes of mtDNA in the same cell or organism is rare and may appear in length or site variation.
A.W.S. Hilsdorf, J.E. Krieger
doaj   +1 more source

Whole genome phylogeny for 21 Drosophila species using predicted 2b-RAD fragments [PDF]

open access: yesPeerJ, 2013
Type IIB restriction endonucleases are site-specific endonucleases that cut both strands of double-stranded DNA upstream and downstream of their recognition sequences.
Arun S. Seetharam, Gary W. Stuart
doaj   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Critical behavior in reaction-diffusion systems exhibiting absorbing phase transition [PDF]

open access: yes, 2003
Phase transitions of reaction-diffusion systems with site occupation restriction and with particle creation that requires n>1 parents and where explicit diffusion of single particles (A) exists are reviewed.
Odor, Geza
core   +4 more sources

insilico.mutagenesis: a primer selection tool designed for sequence scanning applications used in directed evolution experiments

open access: yesBioTechniques, 2005
Several primer prediction programs have been developed for a variety of applications. However, none of these tools allows the prediction of a large set of primers for whole gene site-directed mutagenesis experiments using the megaprimer method. We report
Ulrich Krauss, Thorsten Eggert
doaj   +1 more source

SUMO-interacting motifs of human TRIM5α are important for antiviral activity. [PDF]

open access: yesPLoS Pathogens, 2011
Human TRIM5α potently restricts particular strains of murine leukemia viruses (the so-called N-tropic strains) but not others (the B- or NB-tropic strains) during early stages of infection.
Gloria Arriagada   +2 more
doaj   +1 more source

Restriction Site Extension PCR: A Novel Method for High-Throughput Characterization of Tagged DNA Fragments and Genome Walking

open access: yesPLoS ONE, 2010
Background Insertion mutant isolation and characterization are extremely valuable for linking genes to physiological function. Once an insertion mutant phenotype is identified, the challenge is to isolate the responsible gene.
Jiabing Ji, J. Braam
semanticscholar   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Insights into antibody catalysis: Structure of an oxygenation catalyst at 1.9-Å resolution [PDF]

open access: yes, 1996
The x-ray crystal structures of the sulfide oxidase antibody 28B4 and of antibody 28B4 complexed with hapten have been solved at 2.2-Å and 1.9-Å resolution, respectively.
Hsieh-Wilson, Linda C.   +2 more
core  

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