The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
Summary: tRNA restriction by anticodon nucleases underlies cellular stress responses and self-nonself discrimination in a wide range of taxa. Anticodon breakage inhibits protein synthesis, which, in turn, results in growth arrest or cell death.
Anupam K. Chakravarty+3 more
doaj
Investigation of phylogenetic relationships within Saxifraga diversifolia complex (Saxifragaceae) based on restriction-site associated DNA sequence markers. [PDF]
Yuan R+6 more
europepmc +1 more source
Transformation of chloroplasts with thepsaB gene encoding a polypeptide of the photosystem I reaction center [PDF]
A chloroplast photosystem I reaction center mutation.ac-u-g-2.3. ofChlamydomonas reinhardtii has been complemented with a wild typepsaB gene to restore photosynthetic competence.
Bingham, Scott E.+2 more
core +1 more source
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Golden EGG, a simplified Golden Gate cloning system to assemble multiple fragments
The Golden Gate method is an efficient tool for seamless assembly of multiple DNA fragments, which uses Type IIS restriction endonucleases, cleaving the DNA outside of their recognition site to release DNA parts from PCR fragments or entry clones, thus ...
János Barnabás Biró+6 more
doaj +1 more source
Association analysis of production traits of Japanese quail (Coturnix japonica) using restriction-site associated DNA sequencing. [PDF]
Haqani MI+4 more
europepmc +1 more source
The cleavage site of the restriction endonuclease Ava II [PDF]
J. Gregor Sutcliffe, George M. Church
openalex +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang+8 more
wiley +1 more source
Reference-Based Restriction-Site-Associated DNA Sequencing Data Are Useful for Species Delineation in a Recently Diverged Asexually Reproducing Species Complex (Parmeliaceae, Ascomycota). [PDF]
Barcenas-Peña A+5 more
europepmc +1 more source