Results 141 to 150 of about 1,152,156 (344)

Nature of {varphi}X174 Linear DNA from a DNA Ligase-Defective Host [PDF]

open access: yes, 1974
Linear DNAs have been prepared from {varphi}X phage and from {varphi}X RF II (double-stranded circular form of {varphi}X DNA, formed during infection and nicked in one or both strands) molecules derived from infection at the restrictive temperature of ...
Miller, Lois K., Sinsheimer, Robert L.
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Low rate of point mutation in the mtDNA noncoding fragment of Hypericum taxa [PDF]

open access: yes, 2012
Background and Purpose: Contrary to a major impact of phylogenetic studies on humans and animals, application of the mitochondrial DNA (mtDNA) analysis in plant phylogeny research is rather sporadic due to its high rate of rearrangments and low rate of ...
ANTONELA LEKIĆ   +7 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Gabriel-Ulmer duality for topoi and its relation with site presentations

open access: yes, 2019
Let $\kappa$ be a regular cardinal. We study Gabriel-Ulmer duality when one restricts the 2-category of locally $\kappa$-presentable categories with $\kappa$-accessible right adjoints to its locally full sub-2-category of $\kappa$-presentable ...
Di Liberti, Ivan, González, Julia Ramos
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Restriction site-associated DNA sequencing technologies as an alternative to low-density SNP chips for genomic selection: a simulation study in layer chickens. [PDF]

open access: yesBMC Genomics, 2023
Herry F   +10 more
europepmc   +1 more source

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