Results 41 to 50 of about 1,093,792 (283)
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
A strategy for seamless cloning of large DNA fragments from Streptomyces
BioTechniques, 2015 We report a novel method for the seamless cloning of large DNA fragments (SCLF) of up to 44 kb or larger from Streptomyces chromosomal DNA. SCLF is based on homologous recombination in Streptomyces and is easy to perform. The strategy of SCLF is to flank
Jun Huang +5 more
doaj +1 more source
On the Functional Integral Theory of Systems with Kinematical Interaction
, 1998 We propose a systematic way to investigate the low-temperature thermodynamic properties of quantum spin systems subject to the restriction that only a finite number of bosons may occupy a single lattice site.
Arovas +12 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
A Method for Introducing Mutations into Large Vectors
Chinese Journal of Lung Cancer, 2014 Background and objective In vitro site-directed mutagenesis is a routine technique in molecular biology labs. However, although there are numbers of related methods available, most of these methods are not suitable for introducing mutations into large ...
Fanrong MENG +3 more
doaj +1 more source
BioTechniques, 2009 Existing methods for site-directed plasmid mutagenesis are restrained by the small spectrum of modifications that can be introduced by mutagenic primers and the amplicon size limitations of in vitro DNA synthesis.
Stephan Noll +4 more
doaj +1 more source
Historical Aspects of Restriction Endonucleases as Intelligent Scissors for Genetic Engineering
Fermentation, 2023 Restriction endonucleases are a component of restriction–modification systems, where the main biological function is to protect bacterial cells from incoming foreign DNA molecules.
Irina V. Alekseeva, Nikita A. Kuznetsov
doaj +1 more source
Valuing conservation benefits of an offshore marine protected area [PDF]
, 2014 Increasing anthropogenic pressure in the offshore marine environment highlights the need for improved management and conservation of offshore ecosystems.
Atkins, Jonathan P. +4 more
core +4 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Direct amplification of nodD from community DNA reveals the genetic diversity of Rhizobium leguminosarum in soil [PDF]
, 2001 Sequences of nodD, a gene found only in rhizobia, were amplified from total community DNA isolated from a pasture soil. The polymerase chain reaction (PCR) primers used, Y5 and Y6, match nodD from Rhizobium leguminosarum biovar trifolii, R. leguminosarum
Adolphe Zeze +34 more
core +1 more source