Results 51 to 60 of about 1,179,472 (345)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis +13 more
wiley +1 more source
A Method for Introducing Mutations into Large Vectors
Chinese Journal of Lung Cancer, 2014 Background and objective In vitro site-directed mutagenesis is a routine technique in molecular biology labs. However, although there are numbers of related methods available, most of these methods are not suitable for introducing mutations into large ...
Fanrong MENG +3 more
doaj +1 more source
BioTechniques, 2009 Existing methods for site-directed plasmid mutagenesis are restrained by the small spectrum of modifications that can be introduced by mutagenic primers and the amplicon size limitations of in vitro DNA synthesis.
Stephan Noll +4 more
doaj +1 more source
Sandpiles with height restrictions
, 2002 We study stochastic sandpile models with a height restriction in one and two dimensions. A site can topple if it has a height of two, as in Manna's model, but, in contrast to previously studied sandpiles, here the height (or number of particles per site),
A. Chessa +30 more
core +1 more source
Parent‐to‐Child Information Disclosure in Pediatric Oncology
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor +12 more
wiley +1 more source
Effects of mutations in phage restriction sites during escape from restriction–modification [PDF]
Biology Letters, 2017 Restriction–modification systems are widespread genetic elements that protect bacteria from bacteriophage infections by recognizing and cleaving heterologous DNA at short, well-defined sequences called restriction sites. Bioinformatic evidence shows that restriction sites are significantly underrepresented in bacteriophage genomes, presumably because ...
Maroš Pleška, Călin C. Guet
openaire +2 more sources
Highly specific PCR-RFLP assays for karyotyping the widespread 2Rb inversion in malaria vectors of the Anopheles gambiae complex [PDF]
, 2020 Background: Chromosomal inversion polymorphisms play a role in adaptation to heterogeneous environments. Inversion polymorphisms are implicated in the very high ecological flexibility of the three main malaria vector species of the Afrotropical Anopheles
Besansky, N. J. +10 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez +13 more
wiley +1 more source
Retrofitting the BAC cloning vector pBeloBAC11 by the insertion of a mutant loxP site
BMC Research Notes, 2017 Objective Human genomic libraries constructed in bacterial artificial chromosome vectors were utilized to make physical maps of all 23-chromosome pairs and as the templates for DNA sequencing to aid in the completion of the Human Genome Project. The goal
Jonathon S. Coren
doaj +1 more source
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources