Results 181 to 190 of about 15,555 (263)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Continuous Flow LVAD Support in Restrictive and Obstructive Cardiomyopathies: An INTERMACS Registry Report [PDF]

, 2015
Daniel J. Goldstein, Snehal R. Patel, S.L. Myers, David C. Naftel, James K. Kirklin   +4 more
openalex   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

cTnIR193H restrictive cardiomyopathy mice satisfy high-energy metabolic demands through regulating glucose metabolism. [PDF]

Genes Dis
Luo M, Liu L, Yuan W, Quan J, Li M, Tian J.   +5 more
europepmc   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

Characteristics, cost/effect consideration of clinical examinations, and construction of machine learning models of restrictive cardiomyopathy: insights from Peking Union Medical College Hospital. [PDF]

Int J Surg
Chen AT, Fang L, Lin X, Chen W.
europepmc   +1 more source

A Case of Idiopathic Restrictive Cardiomyopathy

, 1990
Ki Y. Chung, Ki Byoung Nam, Kwang Kon Ko, Myoung Mook Lee, Young Bae Park, Yun Shik Choi, Jung Don Seo, Young Woo Lee   +7 more
openalex   +1 more source

Idiopathic restrictive cardiomyopathy in childhood: A diastolic disorder characterized by delayed relaxation [PDF]

, 1996
Marc Gewillig, Luc Mertens, Philippe Moerman, M Dumoulin   +3 more
openalex   +1 more source

Unveiling sex dimorphism in the healthy cardiac anatomy: Fundamental differences between male and female heart shapes

The Journal of Physiology, EarlyView.
Abstract figure legend We present a shape modelling‐based morphological analysis of sex differences in cardiac anatomy. We conduct our analysis on 456 healthy subjects from the UK Biobank (227M/229F) to uncover sex‐based differences in healthy cardiac morphology.
Beatrice Moscoloni, Cameron Beeche, Julio A. Chirinos, Patrick Segers, Mathias Peirlinck   +4 more
wiley   +1 more source

Restrictive Cardiomyopathy: Contemporary Insights into Pathophysiology, Diagnostic Complexity, and Evolving Therapeutic Perspectives

R Munoz, D Ramirez, Ángel Alemán Márquez, D. Hernandez, Oswald Gerardo Mauricio Cruz, A. Esparza, Brenna Costa da Silva, Katia Gabriela Silva Esquivel, Miguel Á. Contreras, C Curiel, S. Reyes, Centro Universitario de Estudios de la Salud de Aguascalientes. Aguascalientes, Mexico., Benito Montoya Silva, Universidad Cuauhtemoc Aguascalientes. Aguascalientes, Mexico., Katia Gabriela Silva Esquivel, Universidad Cuauhtemoc Aguascalientes. Aguascalientes, Mexico., Miguel Castellanos Contreras, Universidad de Guadalajara. Guadalajara, Jalisco, Mexico., Carlos Alfonso Martín Olguín Curiel, Universidad del Valle de Atemajac. Mexico., Shaili Sajaf Alonso Reyes, Universidad Autónoma de Aguascalientes. Aguascalientes, Mexico.   +21 more
openalex   +2 more sources