Results 111 to 120 of about 616,172 (304)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Comparison of coercive practices in worldwide mental healthcare: overcoming difficulties resulting from variations in monitoring strategies

BJPsych Open
Background Coercive or restrictive practices such as compulsory admission, involuntary medication, seclusion and restraint impinge on individual autonomy.
Martha K. Savage, Peter Lepping, Giles Newton-Howes, Richard Arnold, Vincent S. Staggs, Steven Kisely, Toshio Hasegawa, Keith S. Reid, Eric O. Noorthoorn   +8 more
doaj   +1 more source

Children's rights and restrictive measures during the COVID-19 pandemic: implications for politicians, mental health experts and society. [PDF]

Child Adolesc Psychiatry Ment Health, 2023
Fegert JM, Ludwig-Walz H, Witt A, Bujard M.   +3 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

How to sanction international wrongdoing? The design of EU restrictive measures. [PDF]

Rev Int Organ, 2023
Meissner K.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

"Border closure only increased precariousness": a qualitative analysis of the effects of restrictive measures during the COVID-19 pandemic on Venezuelan's health and human rights in South America. [PDF]

BMC Public Health, 2023
Rocha-Jimenez T, Olivari C, Martínez A, Knipper M, Cabieses B.   +4 more
europepmc   +1 more source

Opinion Analysis: Bargaining in the Shadow of Equitable Apportionment [PDF]

, 2014
This master’s thesis concerns three different areas in the field of fault detection in photovoltaic systems.Previous studies have concerned homogeneous systems with a large set of parameters being observed,while this study is focused on a more ...
Longest, Ryke
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Navigating the Labyrinth of Jurisdiction in Restrictive Measures Cases: Neves 77 Solutions (C-351/22)

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2025 10(3), 555-577 | Article | (Table of Contents) 1. Introduction – 2. Facts of the case and questions referred – 3. Opinion of Advocate General Ćapeta – 4. Judgment of the Court –
Christian Breitler
doaj   +1 more source