Results 181 to 190 of about 614,582 (348)

The impact of COVID-19 perceived threat and restrictive measures on mental health in Italy, Spain, New York, and Hong Kong: An international multisite study. [PDF]

Front Psychol, 2022
Vagnini D, Hou WK, Hougen C, Cano A, Bonanomi A, Facchin F, Molgora S, Pagnini F, Saita E.   +8 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Community feedbacks on COVID-19 restrictive measures and health risk management decolonization perspectives: a socio-anthropological study

, 2023
Genda E, Muhindo JB, Cibogo NF, Bahizire MR, Antoine-Moussiaux N, Coppieters Y, Irenge CA, Bushenyula PK.   +7 more
europepmc   +1 more source

Impact of the COVID-19 pandemic and restrictive measures on acute appendicitis: Do not let your guard down.

J Minim Access Surg, 2022
Herrera JJ, Arrechea R, Mihura M, Bregante M, Medina JP, Pirchi DE.   +5 more
europepmc   +1 more source

Does Policy Matter? On Governments’ Attempts to Control Unwanted Migration [PDF]

Public policy making on asylum takes place in an environment of intense public scrutiny, strong institutional constraints and international collective action problems.
Eiko R. Thielemann
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Lessons from SARS-CoV-2 Pandemics: How Restrictive Measures Impacted the Trend of Respiratory Infections in Neonates and Infants up to Three Months of Age. [PDF]

Pathogens, 2022
De Rose DU, Caoci S, Auriti C, Maddaloni C, Capolupo I, Salvatori G, Brusco C, Coltella L, Concato C, Russo C, Colagrossi L, Perno CF, Braguglia A, Villani A, Dotta A, Raponi M.   +15 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Impact of Restrictive Measures during the Covid-19 Pandemic on Aerosol Pollution of the Atmosphere of the Moscow Megalopolis. [PDF]

Her Russ Acad Sci, 2021
Popovicheva OB, Chichaeva MA, Kasimov NS.   +2 more
europepmc   +1 more source

The System of Restrictive Measures in View of the Judicial Reform of 1864

, 2018
Ilyukhina Vera A., Pomoschikova Nadezhda V.   +1 more
openalex   +1 more source