Results 111 to 120 of about 464,007 (265)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
AGGRESSION INFLICTED ON AN ADOLESCENT RESULTANT: IMBALANCE IN BASIC HUMAN NEEDS
Objetivo: Descrever as necessidades humanas básicas afetadas em uma adolescente vitimada por agressão por arma branca. Método: O referencial de análise foi a teoria das Necessidades Humanas Básicas, de Horta (1979).
Ana Paula de Assis Sales da Silva +5 more
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Research on the simplified calculation method of non-limit active earth pressure of limited soil mass in adjacent foundation pits. [PDF]
Zhang Z +6 more
europepmc +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Kinematic determinants of take-off performance in elite and sub-elite male long jumpers: a competition-based two-dimensional motion analysis. [PDF]
Wei P, Yuan T, Xie Z.
europepmc +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Correction: Long-term random sampling confirms high-use areas and indicates declining abundance of juvenile smalltooth sawfish (Pristis pectinata) in Charlotte Harbor, Florida. [PDF]
Farmer NA +7 more
europepmc +1 more source

