Results 111 to 120 of about 92,194 (291)

Resveratrol-βcd inhibited premature ovarian insufficiency progression by regulating granulosa cell autophagy

open access: yesJournal of Ovarian Research
Background The ovarian environment of premature ovarian insufficiency (POI) patients exhibits immune dysregulation, which leads to excessive secretion of numerous proinflammatory cytokines that affect ovarian function.
Bingbing Hu, Xiushuang Zheng, Wei Zhang
doaj   +1 more source

Enhancing antioxidant capacity of chitosan‐caseinophosphopeptides nanocomplexes‐stabilized Pickering emulsion by incorporating theaflavin‐3,3′‐digallate

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Emulsions are common colloidal systems in food products, yet their quality is frequently compromised by lipid oxidation. We have recently developed a new Pickering emulsion stabilized by genipin cross‐linked chitosan‐caseinophosphopeptides nanocomplexes (GCNs).
Yike Jiang   +3 more
wiley   +1 more source

Resveratrol Induces Myotube Development by Altering Circadian Metabolism via the SIRT1-AMPK-PP2A Axis

open access: yesCells
Resveratrol is a polyphenol known to have metabolic as well as circadian effects. However, there is little information regarding the metabolic and circadian effect of resveratrol on muscle cells.
Natalie Avital-Cohen   +2 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng   +14 more
wiley   +1 more source

Phosphatidylinositol-3-Kinase Is Involved in the Antihyperglycemic Effect Induced by Resveratrol in Streptozotocin-Induced Diabetic Rats

open access: yes, 2008
Resveratrol, a polyphenolic substance found in grape skin, is proposed to account in part for the protective effect of red wine in the cardiovascular system. The aim of the present study is to investigate the action and possible mechanisms of resveratrol-
CHI, TZONG-CHERNG;KUO, TZONG-FU;LEE, SHOEI-SHENG;CHENG, JUEI-TANG;SU, MING-JAI   +1 more
core  

Resveratrol- and Rapamycin-induced Morphological Changes to Human Epithelial Colon Cancer DLD-1 Cells [PDF]

open access: yes, 2008
The prosperous polyphenol resveratrol have shown healthy benefits and anti-cancer properties, but the effect of resveratrol on cell morphology is less studied.
Durhuus, Jon Ambæk, Fang, Ping
core  

Senotherapeutics for Knee Osteoarthritis

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman   +6 more
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li   +6 more
wiley   +1 more source

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