Results 121 to 130 of about 15,148 (196)

<i>RET</i>-Targeted Neoadjuvant Therapy Enables Curative Surgery in an Ultra-Elderly Patient With Recurrent Colon Cancer Harboring a CCDC6-RET Fusion. [PDF]

JCO Precis Oncol
Jin T, Cricri M, Chen X, He J, Liu Y.
europepmc   +1 more source

The Role of Variance Risk Premium in Derivative Pricing: Modeling, Estimation and Impact

Journal of Futures Markets, Volume 46, Issue 11, Page 1811-1823, November 2026.
ABSTRACT This paper estimates a model where variance risk premiums (VRP) is not fully explained by equity risk premiums (ERP). This separation can be detected thanks to a new breed of GARCH models with enough innovations to disconnect returns from variances. This type of risk‐neutralization is compatible with continuous‐time settings.
Marcos Escobar‐Anel, Lars Stentoft, Xize Ye   +2 more
wiley   +1 more source

Acute β-cell failure induced by selpercatinib in RET fusion-positive non-small cell lung cancer: A case report. [PDF]

Respir Med Case Rep
Tsukao H, Kojima R, Nakanishi S, Miyanishi Y, Fujii Y, Yamaguchi W, Nakaya J, Kojima T.   +7 more
europepmc   +1 more source

Lifetime Estimation of Blade Erosion Using Rain Erosion Test Data With Different Analysis Methods

Wind Energy, Volume 29, Issue 11, November 2026.
ABSTRACT Lifetime estimation regarding leading‐edge erosion of wind turbine blades involves a series of mathematical and statistical procedures, including regression fitting, tolerance interval formulation, and weathering modeling approaches. This work investigates the intermediate steps in the fatigue assessment process and the associated sources of ...
J. E. Simon, A. Bajpai, N. F.‐J. Johansen, Á. Hannesdóttir, C. B. Hasager   +4 more
wiley   +1 more source

Neoadjuvant Selpercatinib for Stage IIIA Primary Pulmonary Adenocarcinoma With RET Fusion: A Case Report. [PDF]

Respirol Case Rep
Cui Z, Hu Y, Zhao J, Mu C, Li C.
europepmc   +1 more source

The variability of giraffe skull morphology

Journal of Anatomy, Volume 249, Issue 5, Page 1068-1086, November 2026.
What does giraffe skull shape tell us about their development and evolution? Abstract Giraffe (Giraffa spp.) are among the most unique and charismatic extant animals, largely due to their distinct morphology. The evolutionary and developmental origin of ossicones is a key factor in giraffid biology, yet other features building their characteristic head
Nikolaos Kargopoulos, Jesús Marugán‐Lobón, Anusuya Chinsamy‐Turan, Bernard R. Agwanda, Michael Butler Brown, Stephanie Fennessy, Sara Ferguson, Rigardt Hoffman, Fredrick Lala, Arthur Muneza, Ogeto Mwebi, Moses Otiende, Alice Petzold, Sven Winter, Abdoul Razack Moussa Zabeirou, Julian Fennessy   +15 more
wiley   +1 more source

Beyond the Monolayer: Leveraging 3D Culture Systems to Decode Mechanisms of Drug Resistance and Therapeutic Vulnerabilities in Colorectal Cancer

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Two‐dimensional (2D) monolayer cultures remain the workhorse of colorectal cancer (CRC) research and high‐throughput screening (HTS), yet they poorly recapitulate tissue architecture, extracellular matrix (ECM) cues, metabolic gradients, and multicellular heterogeneity that govern drug response in vivo. Over the past decade, three‐dimensional (
Sarah J. Harmych, Bhuminder Singh
wiley   +1 more source

Safety and effectiveness of selpercatinib in patients with RET fusion-positive non-small cell lung cancer in real-world clinical practice: a postmarketing study in Japan. [PDF]

Jpn J Clin Oncol
Chen Y, Mori J, Wakabayashi S, Urayama KY.   +3 more
europepmc   +1 more source

Next‐Generation Sequencing‐Based Molecular Profiling and Management of Advanced Solid Tumors: A Real‐World Experience in a Community‐Based Academic Cancer Center

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Advances in molecular and cell biology have led to a paradigm shift in cancer management. We implemented next‐generation sequencing (NGS) at our community‐based academic cancer center over a decade ago. We sought to optimize the use of genomics and understand its impact in identifying actionable genomic alterations to determine ...
Gayathri Moorthy, Annette Sereika, Karen Kaul, Megan Parilla, Mir B. Alikhan, Michael Bouma, Dyson Wake, Peter J. Hulick, Henry M. Dunnenberger, Linda M. Sabatini, Mathew Yang, Kathy A. Mangold, Erin Proctor, Nicholas Evans, Nicholas Miller, Donald L. Helseth Jr, Darryck Maurer, Justin Brueck, Janardan Khandekar, Bruce Brockstein   +19 more
wiley   +1 more source

Case Report: Complete pathologic response to neoadjuvant immunotherapy-chemotherapy in a patient with RET fusion-positive non-small cell lung cancer. [PDF]

Front Oncol
Wang Y, Zhang Y, Cai C, Liu X, Ren S, Zhou S.   +5 more
europepmc   +1 more source