Results 181 to 190 of about 53,193 (289)

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 1, Page 26-46, March 2026.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan   +3 more
wiley   +1 more source

RET Gene Fusions in Malignancies of the Thyroid and Other Tissues [PDF]

open access: gold, 2020
Massimo Santoro   +3 more
openalex   +1 more source

Treatment of Advanced Non-Small Cell Lung Cancer with RET Fusions: Reality and Hopes [PDF]

open access: gold, 2023
Danilo Rocco   +4 more
openalex   +1 more source

Signal Peptide Engineering and Codon Optimization to Enhance α‐Gal A Activity for rAAV Gene Therapy of Fabry Disease

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Fabry disease is an X‐linked lysosomal storage disorder caused by mutations in the GLA gene, leading to deficient α‐galactosidase A (α‐Gal A) activity and pathological accumulation of globotriaosylceramide (Gb3) and globotriaosylsphingosine (Lyso‐Gb3) in various organs.
Siwu He   +15 more
wiley   +1 more source

Photo‐Excitations in Halide Perovskites: Where Do Simulations and Experiments Meet?

open access: yesLaser &Photonics Reviews, Volume 20, Issue 6, 18 March 2026.
Aiming to bridge the gap between simulations and measurements of light–matter couplings and photo‐excitations in new functional materials, this perspective highlights insights and bottlenecks of state‐of‐the‐art experimental and theoretical methods (2D electronic spectroscopy vs.
Muhammad Sufyan Ramzan   +5 more
wiley   +1 more source

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