Results 211 to 220 of about 939,495 (280)

Tumor Lysis Syndrome Induced by Selpercatinib in Rearranged During Transfection (RET) Fusion-Positive Non-Small-Cell Lung Cancer. [PDF]

Cureus
Sagawa S, Tomoda Y, Shikama J, Awaya Y.
europepmc   +1 more source

Envonalkib Versus Crizotinib in Treatment‐Naive ALK‐Positive Non‐Small Cell Lung Cancer: Final Efficacy and Biomarker Analyses of the Randomized Phase III Study

MedComm, Volume 7, Issue 10, October 2026.
Envonalkib provides robust and durable benefit in treatment‐naïve ALK‐positive NSCLC, with median PFS of 30.4 months versus 12.0 months for crizotinib. Exploratory biomarker analyses showed that concurrent driver alterations and p53 pathway dysfunction reduce treatment efficacy.
Jie Huang, Yuanyuan Wang, Haishuang Sun, Jie Min, Nong Yang, Qitao Yu, Ying Cheng, Yanqiu Zhao, Manxiang Li, Hong Chen, Shouan Ren, Jianying Zhou, Wu Zhuang, Xintian Qin, Lejie Cao, Yan Yu, Jian Zhang, Jianxing He, Jifeng Feng, Hao Yu, Lin Zhang, Xinyuan Zhao, Wenfeng Fang, Jing Li, Li Zhang, Yunpeng Yang   +25 more
wiley   +1 more source

Salivary gland secretory carcinoma with an ETV6::RET fusion: A case report. [PDF]

Biomed Rep
Ishihara A, Kuwabara H, Yasuda E, Jinnin T, Higashino M, Nagao T, Haginomori SI, Hirose Y.   +7 more
europepmc   +1 more source

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan, Ke Tang, Linglong Wang, Qin Tian, Mingwei Zheng, Cheng Qian, Limei Liu   +6 more
wiley   +1 more source

Erratum to Acute β-cell failure induced by selpercatinib in RET fusion-positive non-small cell lung cancer: A case report [Respir. Med. Case Rep. 59 (2026) 102372]. [PDF]

Respir Med Case Rep
Tsukao H, Kojima R, Nakanishi S, Miyanishi Y, Fujii Y, Yamaguchi W, Nakaya J, Kojima T.   +7 more
europepmc   +1 more source

Applying a Pareto‐Based Efficiency Frontier to Inform Value‐Based Pricing for Gaucher Disease Therapies in Brazil

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Gaucher disease (GD) requires lifelong high‐cost treatment within the Brazilian Unified Health System (SUS). In Brazil, treatment eligibility and monitoring are defined by Clinical Protocol and Therapeutic Guidelines (PCDT), while pharmaceutical prices are regulated by the Drug Market Regulation Chamber (CMED).
Marcus Carvalho Borin, Ludmila Peres Gargano, Francisco de Assis Acurcio, Juliana Álvares‐Teodoro, Augusto Afonso Guerra Junior   +4 more
wiley   +1 more source

Induction therapy of pralsetinib followed by conversion surgery for unresectable locally advanced non-small cell lung cancer with the rearranged during transfection (RET) fusion gene mutation: protocol for a single-arm phase II prospective trial (the SALVAGE-P trial). [PDF]

J Thorac Dis
Deng HY, Qiu XM, Li L, Tang XJ, Zhou Q.
europepmc   +1 more source

Internal Structure, Kinematics, and Prehistory of Frozen Debris Lobe‐A (FDL‐A), Brooks Range, Alaska

Permafrost and Periglacial Processes, Volume 37, Issue 4, Page 645-667, October/December 2026.
ABSTRACT Frozen Debris Lobe‐A (FDL‐A)—one of hundreds of FDLs in the Brooks Range of northern Alaska—is a slow‐moving landslide in permafrost that has been the subject of research since 2008 due to its close proximity to the Dalton Highway. Here, we synthesize more than a decade's worth of climate and surface measurements of monitored FDLs, and the ...
Margaret M. Darrow, Esther L. Babcock, Ben A. Leshchinsky   +2 more
wiley   +1 more source

Long-term complete remission with immunotherapy in advanced RET fusion-positive NSCLC with brain metastases: a case report and literature review. [PDF]

Front Oncol
Shang S, Qin M, Zhang S.
europepmc   +1 more source

How Should We Identify Home‐ and Community‐Based Services (HCBS) in Medicaid Claims Data? An Evaluation and Synthesis of Algorithms

Health Services Research, Volume 61, Issue 5, October 2026.
ABSTRACT Objective To assess existing algorithms for measuring Home‐ and Community‐Based Services (HCBS) in Medicaid claims, and to develop and evaluate a unified, modified algorithm. Study Setting and Design Using Transformed Medicaid Statistical Information System Analytic Files (TAF), we compared two existing algorithms for identifying and ...
Vimbainashe Dihwa, Eric T. Roberts, Eliza Macneal, Kenton J. Johnston, Ari Ne′eman   +4 more
wiley   +1 more source