Results 61 to 70 of about 342,765 (293)

Pipeline

, 2007
Twice monthly.; Vol. 1, issue 1 (Feb. 14, 2007)-; An electronic publication reporting state and local issues and program initiatives of special interest to Ohio's MRDD community.
Ohio. Dept. of Mental Retardation and Developmental Disabilities.
core  

Fatigue Damage Mechanism-Based Dependent Modeling With Stochastic Degradation and Random Shocks

IEEE Access, 2018
This paper proposes a dependent modeling method for reliability estimation of metal structures under constant amplitude loading and random shocks considering the nonlinear damage accumulation mechanism.
Dan Xu, Jiaolan He, Shaobo Sui, Shan Jiang, Wei Zhang   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Evaluation of tooth physiological characteristics based on PS-OCT

Journal of Innovative Optical Health Sciences
Accurate and early evaluation of dental physiological characteristics is essential for effective disease detection and management. Polarization-sensitive optical coherence tomography (PS-OCT) is a noninvasive high-resolution imaging technique that can ...
Songwen Xu, Weike Wang, Di Yang, Xiaoyi Zhao, Hao Liu, Yanmei Liang   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Mental retardation

Jornal de Pediatria, 2004
This paper describes recent advances in the neurobiology of mental retardation, emphasizing new diagnostic resources provided by cytogenetics, molecular testing, and neuroimaging.MEDLINE (January 2000 through October 2003), using the following key words: mental retardation, developmental disability, child, and adolescent.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Study on the performance of nanoparticle-modified PVDF membrane in delaying membrane aging

Open Chemistry
With an emphasis on improving the membrane’s long-term durability and filtering efficiency, this study examines how well nanoparticle-modified polyvinylidene fluoride (PVDF) membranes perform in postponing membrane aging.
Lin Fuxing
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance

PCN Reports
Aim In the DSM‐5, it is specified that severe cases of major depressive disorder with anxious distress (ANXD) may be accompanied with motor agitation.
Yu Tamada, Takeshi Inoue, Atsushi Sekine, Hiroyuki Toda, Minoru Takeshima, Masaaki Sasaki, Yota Fujimura, Susumu Ohmae   +7 more
doaj   +1 more source