Results 61 to 70 of about 10,171 (216)

Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance

open access: yesPCN Reports
Aim In the DSM‐5, it is specified that severe cases of major depressive disorder with anxious distress (ANXD) may be accompanied with motor agitation.
Yu Tamada   +7 more
doaj   +1 more source

Influences of flocculant and retarder on solidification efficiency of cement in treatment of dredged mud slurry

open access: yesYantu gongcheng xuebao, 2019
It is usually necessary to build a working platform on the surface of the dumping site of dredged mud slurry for the purpose of rapid improvement of the dumping site so as to shorten the period of land occupation.
ZHANG Rong-jun 1, DONG Chao-qiang 1, ZHENG Jun-jie 1, LU Zhan 2
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Maduración visual retardada

open access: yesRevista Cubana de Oftalmología
Retraso en la maduración visual es el término utilizado para describir aquellos niños con incapacidad de fijar o seguir objetos en el ambiente, que no responden ante la proximidad de un objeto amenazante o un destello de luz, por ejemplo, abrir y cerrar ...
Yolelvis Monfort Estévez   +1 more
doaj  

Branched-chain and odd-numbered fatty acids and aldehydes in the nervous system of a patient with deranged vitamin B12 metabolism

open access: yesJournal of Lipid Research, 1973
A mixture of isomers of methylhexadecanoic acid was isolated from glycerolipids of brain, spinal cord, and sciatic nerve of a patient who died from methylmalonic aciduria, a disease in which vitamin B12 is not converted to deoxyadenosyl B12.
Yasuo Kishimoto   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Isolation and characterization of glucosylsphingosine from Gaucher's spleen

open access: yesJournal of Lipid Research, 1974
Glucosylsphingosine has been isolated for the first time as a natural constituent from Gaucher's spleen. On thinlayer chromatography, it migrates with authentic glucosylsphingosine, yielding a positive color reaction with ninhydrin for the amino group ...
Srinivasa S. Raghavan   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Quantitative analysis of brain galactosylceramides by high performance liquid chromatography of their perbenzoyl derivatives

open access: yesJournal of Lipid Research, 1976
A high performance liquid chromatographic (HPLC) method for analysis of galactosylceramides as their benzoyl derivatives has been devised. Samples containing 10-150 nmoles of monohexosylceramides are benzoylated by heating for 60 min at 60 ° C in 0.5 ml ...
E H McCluer, J E Evans
doaj   +1 more source

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