Results 81 to 90 of about 1,733,137 (338)

Evaluation of a leadership development program to enhance university staff and student resilience

open access: yesJournal of Teaching and Learning for Graduate Employability, 2019
University life presents challenges that can negatively affect the health and wellbeing of students and staff. Resilience is critical to managing challenges and thus is increasingly viewed as important for university students, graduates and employees. To
Margo Lee Brewer   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

MicroRNA sequence codes for small extracellular vesicle release and cellular retention

open access: yesNature, 2021
Ruben Garcia-Martin   +7 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Modified support phase appliance after twin block therapy

open access: yesSRM Journal of Research in Dental Sciences, 2014
Buccal segment occlusion is the cornerstone of stability after correction of Class II malocclusion using a twin block appliance. The following short communication is a modification of Clark′s original support phase appliance, to achieve better retention ...
Gautham Sivamurthy   +2 more
doaj   +1 more source

Retention as an integrated biodiversity conservation approach for continuous-cover forestry in Europe

open access: yesAmbio, 2019
Retention forestry implies that biological legacies like dead and living trees are deliberately selected and retained beyond harvesting cycles to benefit biodiversity and ecosystem functioning. This model has been applied for several decades in even-aged,
L. Gustafsson   +19 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Gadolinium Retention: A Research Roadmap from the 2018 NIH/ACR/RSNA Workshop on Gadolinium Chelates.

open access: yesRadiology, 2018
Gadolinium-based contrast agents (GBCAs) have revolutionized MRI, enabling physicians to obtain crucial life-saving medical information that often cannot be obtained with other imaging modalities.
R. McDonald   +12 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy