Results 81 to 90 of about 3,371,054 (410)

The METLIN small molecule dataset for machine learning-based retention time prediction

open access: yesNature Communications, 2019
Machine learning has been extensively applied in small molecule analysis to predict a wide range of molecular properties and processes including mass spectrometry fragmentation or chromatographic retention time.
Xavier Domingo-Almenara   +9 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Why One and Two Do Not Make Three: Dictionary Form Revisited

open access: yesLexikos, 2012
The primary aim of the article is to compare the usefulness of paper and electronic versions of OALDCE7 (Wehmeier 2005) for language encoding, decoding and learning.
Anna Dziemianko
doaj   +1 more source

Switching Cost and Customers Loyalty in the Mobile Phone Market:the Nigerian Experience [PDF]

open access: yes, 2010
Switching cost is one of the most discussed contemporary issues in marketing in attempt to explain consumer behaviour. The present research studied switching cost and its relationships with customer retention, loyalty and satisfaction in the Nigerian ...
Abiodun, A. J., Oyeniyi, Omotayo
core  

Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme

open access: yesBMJ Open, 2017
Background Substantial amounts of public funds are invested in health research worldwide. Publicly funded randomised controlled trials (RCTs) often recruit participants at a slower than anticipated rate.
S. Walters   +10 more
semanticscholar   +1 more source

Alaska’s Judicial Retention Elections: A Comparative Analysis [PDF]

open access: yes, 2017
The results of recent judicial retention elections in Alaska, and the recent increase in political activities related to judicial selection in Alaska and many other states, have given rise to concerns about the fates of future Alaska retention candidates.
Klumpp, Albert J.
core   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

The Application of Zeta Potential for the Effective Retention of Titanium Dioxide in Chemically Modified Systems [PDF]

open access: yes, 1971
This study was done to determine how to obtain maximum effective filler retention in a fiber and titanium dioxide system. Retention of fillers in a fibrous system is greatly influenced through the use of high molecular weight polymers.
Clapp, John W.
core   +1 more source

Effect of surface modification on single-walled carbon nanotube retention and transport in saturated and unsaturated porous media [PDF]

open access: yes, 2012
This work investigated the effect of different surface modification methods, including oxidization, surfactant coating, and humic acid coating, on single-walled carbon nanotube (SWNT) stability and their mobility in granular porous media under various ...
Gao, Bin   +4 more
core   +2 more sources

Gadolinium Retention: A Research Roadmap from the 2018 NIH/ACR/RSNA Workshop on Gadolinium Chelates.

open access: yesRadiology, 2018
Gadolinium-based contrast agents (GBCAs) have revolutionized MRI, enabling physicians to obtain crucial life-saving medical information that often cannot be obtained with other imaging modalities.
R. McDonald   +12 more
semanticscholar   +1 more source

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