Results 81 to 90 of about 2,646,331 (287)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Prevention, Retention & Contingency Development Reserve (PRCDR) summary of projects
, 2000 Title from covers of PDF documents (viewed June 21, 2006).; "The Institute for Local Government Administration and Rural Development (ILGARD) at Ohio University prepared this report for the Ohio Department of Job and Family Services in cooperation with ...
Ohio University. Institute for Local Government Administration and Rural Development.
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Can altering the structure of financial support payments aid work retention amongst lone parents? Qualitative evaluation of the In Work Retention Pilot [PDF]
, 2010 Wage supplementations in the form of temporary ‘in-work credits’ have been introduced in recent years for a number of claimant groups entering work, to encourage enhanced work entry and retention rates.
Ray, K. +3 more
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ADMET and DMPKBackground and Purpose: The ligands of the imidazoline and α-adrenergic receptors are mainly imidazoline and guanidine derivatives, known as centrally-acting antihypertensives and compounds with potential use in various neurological disorders.
Slavica Oljacic +5 more
doaj +1 more source
Harm Reduction Journal, 2010 Background Methadone is a synthetic opiate mu receptor agonist that is widely used to substitute for illicit opiates in the management of opiate dependence.
Talib Nazila +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The effectiveness of grade retention as an intervention strategy for academic failure [PDF]
, 2001 Plan BOver the past decade there has been public and political pressure to improve the quality of education. Schools are being encouraged to adopt grade retention policies to help children who are falling behind academically.
Viland, Kelly Rochelle
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Design for Supporting Sustainable Behaviour Retention through Context Change
, 2017 The socio-economic transitions in developing countries and emerging economics have led to consumption behaviour changes in almost every aspect of individuals’ life, resulting inconsumerist lifestyles and growing numbers of social and environmental ...
Chu, Wanjun, Wever, Renee
core +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source