Multistep Synthesis and In Vitro Anticancer Evaluation of 2-Pyrazolyl-Estradiol Derivatives, Pyrazolocoumarin-Estradiol Hybrids and Analogous Compounds [PDF]
Molecules, 2020 Although the hormone independent cytotoxic activity of several estradiol derivatives endowed with a simple substituent at C-2 has been reported so far, 2-heterocyclic and 2,3-condensed analogs are less investigated from both synthetic and pharmacological
Barnabás Molnár +4 more
doaj +5 more sources
Synthesis and Antitumor Evaluation of Novel Hybrids of Phenylsulfonylfuroxan and Estradiol Derivatives [PDF]
ChemistryOpen, 2020 Fifteen novel furoxan‐based nitric oxide (NO) releasing hybrids of estradiol derivatives were synthesized and evaluated in vitro anti‐proliferative activity in MDA‐MB‐231, A2780, Hela and HUVEC cell lines. Most of them displayed potent anti‐proliferative
Qi Wan +7 more
doaj +3 more sources
Retention behaviour of estradiol derivatives in reversed phase HPLC [PDF]
Acta Periodica Technologica, 2005 Retention behaviour ofestradiol derivatives has been studied by the reversed phase HPLC. LiChrosorb RP-18 column end eluents consisting of methanol respectively aceto-nitrile and water in various proportions, were used.
Ačanski Marijana M. +1 more
doaj +2 more sources
Substitutional Diversity-Oriented Synthesis and In Vitro Anticancer Activity of Framework-Integrated Estradiol-Benzisoxazole Chimeras [PDF]
Molecules, 2022 Hybridization of steroids and other pharmacophores often modifies the bioactivity of the parent compounds, improving selectivity and side effect profile.
Ferenc Kovács +5 more
doaj +3 more sources
Chemometric estimation of the retention behavior of selected estradiol derivatives [PDF]
Acta Periodica Technologica, 2015 Quantitative structure-retention relationship (QSRR) analysis has been performed in order to correlate the retention of selected estradiol derivatives with their calculated molecular lipophilicity.
Karadžić Milica Ž. +5 more
doaj +2 more sources
A Sulfuryl Group Transfer Strategy to Selectively Prepare Sulfated Steroids and Isotopically Labelled Derivatives [PDF]
Frontiers in Molecular Biosciences, 2021 The treatment of common steroids: estrone, estradiol, cortisol, and pregnenolone with tributylsulfoammonium betaine (TBSAB) provides a convenient chemoselective conversion of the steroids alcohol/phenol moiety to the corresponding steroidal organosulfate.
Jaber A. Alshehri +2 more
doaj +2 more sources
Normal-phase high performance liquid chromatography of estradiol derivatives on amino- and diol-columns [PDF]
Journal of the Serbian Chemical Society, 2003 The retention behavior of estradiol derivatives was studied by HPLC on chemically bonded polar stationary phases: commercially available amino and diol- columns, as a function of the heptane-propan-1-ol as the mobile phase, when the volume fraction of ...
Ačanski Marijana M.
doaj +3 more sources
Tropical and Subtropical Agroecosystems, 2023 Background: During the last few years the home box transcription factor WUSCHEL (WUS) has been shown to cause dedifferentiation when expressed on somatic cells followed by a production of new stem cells that can lead to somatic embryogenesis or ...
Ana Ly Arroyo Herrera +7 more
doaj +1 more source
Retention behaviour of some estradiol derivatives on alumina in normal phase chromatrography [PDF]
Journal of the Serbian Chemical Society, 2003 The retention constants of variously substituted estradiol derivatives were measured as a function of the composition of various binary mobile phases in order to study the relationship between chemical structure and retention behavior in TLC on alumina ...
Ačanski Marijana M.
doaj +1 more source
SYNTHESIS OF SOME POTENTIAL ANTIESTROGENIC AGENTS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2005 Some novel steroidal arylidene derivatives were synthesized and representative examples were tested for their antiestrogenic activity. The active compounds were subjected for antitumor activity screening.
Gehan Hegazy +2 more
doaj +1 more source