Results 91 to 100 of about 212,634 (323)

Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis [PDF]

, 2017
The effect of a sodium glucose cotransporter 2 inhibitor (SGLT2i) in reducing heart failure hospitalization in the EMPA-REG OUTCOMES trial has raised the possibility of using these agents to treat established heart failure.
De Vecchis, Ferrannini, Fitchett, Francis, Greenberg, Hammon, Heise, Heise, Hirose, Lindner, Neal, Peacock, Rabe, Schmieder, Schneider, Schrier, Schrier, Shimizu, Titze, Titze, Titze, Weinfeld, Zinman   +22 more
core   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Treating Homeless Opioid Dependent Patients with Buprenorphine in an Office-Based Setting [PDF]

, 2007
CONTEXT Although office-based opioid treatment with buprenorphine (OBOT-B) has been successfully implemented in primary care settings in the US, its use has not been reported in homeless patients.
Alford, Daniel P., Cheng, Debbie M., Hohl, Carole A., LaBelle, Colleen T., O'Connell, James J., Richardson, Jessica M., Samet, Jeffrey H.   +6 more
core   +3 more sources

Acute urinary retention in a pre-school girl with constipation

Revista Paulista de Pediatria, 2015
Objective: To report a case of a preschool girl who developed acute urinary retention associated with constipation. Case description: A girl aged six years old presented a 24 h history of inability to urinate.
Guillermo A. Ariza Traslaviña, Luiz Antonio Del Ciampo, Ivan Savioli Ferraz   +2 more
doaj   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

The application of low crude protein wheat-soyabean diets to growing and finishing pigs: 2. The effects on nutrient digestibility, nitrogen excretion, faecal volatile fatty acid concentration and ammonia emission from boars [PDF]

, 2005
peer-reviewedThis study received financial support from Telltech Ltd. (Wicklow, Ireland) and Enterprise Ireland (Dublin, Ireland).Diets containing 132, 152, 183 and 206 g/kg crude protein (CP) were fed to growing and finishing boars to evaluate the ...
Callan, J.J., Henry, R. W., Leek, A. B. G., O'Doherty, John V.   +3 more
core  

The pharmacokinetics of anthocyanins and their metabolites in humans [PDF]

, 2014
Background and Purpose: Anthocyanins are phytochemicals with reported vasoactive bioactivity. However, given their instability at neutral pH, they are presumed to undergo significant degradation and subsequent biotransformation.
Anupongsanugool, Azzini, Bell, Cardona, Cassidy, Cassidy, Czank, Das, Del Rio, Erdman, Ferrars, Forester, Garcia-Alonso, Gonzalez-Barrio, Ichiyanagi, Kay, Kay, Kay, Kim, Kim, Kim, Manach, McGhie, Min, Mink, Miyazawa, Mullen, Nardini, Nardini, Nizamutdinova, Nurmi, Pero, Rodriguez-Mateos, Stalmach, Toromanović, Vane, Vitaglione, Wang, Williamson, Wittemer, Woodward, Woodward, Xu, Zhang, Zhang, Zhang, Zhu   +46 more
core   +1 more source

MANAJEMEN RETENSI URIN PADA LANSIA DI IGD: STUDI KASUS DARI RS PKU MUHAMMADIYAH GAMPING

JPK
Urinary Retention is a condition of inability to urinate even though the bladder is full and this condition is often accompanied by a sensation of pain.
Meisty Anggraeni Meisty, Efi Fibriyanti
doaj   +1 more source

Prolonged Postpartum Persistent Urinary Retention After Cesarean Section: A Case Report and Literature Review

Gynecology Obstetrics & Reproductive Medicine, 2019
We aimed to present a case of urinary retention that develops after caesarean delivery and persists for 33 days. A 35-year-old G4P2 41-week-old pregnant woman applied to our clinic because she could not urinate on the 4th day after cesarean section ...
Recep Erin, Derya Burkankulu Agirbas, Kubra Baki Erin, Deniz Kulaksız   +3 more
doaj   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source