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Generation of ventralized human thalamic organoids with thalamic reticular nucleus
Cell Stem Cell, 2023Human brain organoids provide unique platforms for modeling several aspects of human brain development and pathology. However, current brain organoid systems mostly lack the resolution to recapitulate the development of finer brain structures with subregional identity, including functionally distinct nuclei in the thalamus. Here, we report a method for
Bilal Cakir +2 more
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Projections to the rostral reticular thalamic nucleus in the rat
Experimental Brain Research, 1990Afferent pathways to the rostral reticular thalamic nucleus (Rt) in the rat were studied using anterograde and retrograde lectin tracing techniques, with sensitive immunocytochemical methods. The analysis was carried out to further investigate previously described subregions of the reticular thalamic nucleus, which are related to subdivisions of the ...
Jonathan Cooper
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Thalamic nucleus submedius receives GABAergic projection from thalamic reticular nucleus in the rat
Neuroscience, 2005GABAergic projection from thalamic reticular nucleus to thalamic nucleus submedius in the medial thalamus of the rat was studied by using immunohistochemistry for GABA, retrograde labeling with Fluoro-Gold combined with immunohistochemistry for GABA, and anterograde labeling with biotinylated dextranamine.
Lei Chen
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An anatomical study of the efferent connections of the thalamic reticular nucleus
Experimental Brain Research, 1971A neuro-anatomical investigation into the thalamic reticular nucleus and its connections was made in the albino rat, using the method of retrograde degeneration and the Nauta-Gygax method. The results correspond to the description given by Scheibel and Scheibel and indicate connections of the neurons of the reticular which the principal thalamic nuclei
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Paying attention to the thalamic reticular nucleus
Trends in Neurosciences, 1998The thalamic reticular nucleus can be divided into a number of sectors, each concerned with a different function (sight, touch, hearing, movement or 'limbic' functions). Each sector is connected to more than one thalamic nucleus and to more than one cortical area, and each sector has topographically mapped connections with the thalamus and the cortex ...
R W, Guillery, S L, Feig, D A, Lozsádi
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The Thalamic Reticular Nucleus
2023Abstract The thalamic reticular nucleus (TRN), an entirely GABAergic shell-shaped structure, is reciprocally connected with the thalamus, where it circulates—via the thalamocortical and corticothalamic axons—temporal and multimodal information.
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The Thalamic Reticular Nucleus: More Than a Sensory Nucleus?
The Neuroscientist, 2002Sensory information is routed to the cortex via the thalamus, but despite this sensory bombardment, animals must attend selectively to stimuli that signal danger or opportunity. Sensory input must be filtered, allowing only behaviorally relevant information to capture limited attentional resources.
Kerry, McAlonan, Verity J, Brown
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Thalamic reticular nucleus in the thalamocortical loop
Neuroscience Research, 2020Dynamic binding of different brain areas is critical for various cognitive functions. The thalamic reticular nucleus (TRN) is a GABAergic nucleus that constrains information flow through thalamocortical loop by providing inhibitory innervation to the thalamus.
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