Dowling-Degos Disease with Multiple Seborrheic Keratosis: An Atypical Presentation in Two Siblings. [PDF]
Ankita +4 more
europepmc +1 more source
Advanced Sorbent Materials in Solid‐Phase Extraction: A Decade of Innovation and Future Perspectives
This review systematically summarizes five families of advanced sorbent materials for solid‐phase extraction (SPE): nanocarbons, porous frameworks (MOFs/COFs), smart polymers, biomass‐derived sorbents, and multifunctional composites. Key molecular interactions (π–π stacking, hydrogen bonding, electrostatic attraction, host–guest recognition) are ...
Xingchen Wang +4 more
wiley +1 more source
Dyschromatosis universalis hereditaria: Dermoscopic insights in a patient with intellectual disability. [PDF]
Elizabeth Rosales Martínez Z +3 more
europepmc +1 more source
Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei +5 more
wiley +1 more source
Progressive scattered and reticular pigmentation lesions. [PDF]
Zhou Y +5 more
europepmc +1 more source
CLRN1 Variants in Müller Cells Cause Mitochondrial Dysfunction in USH3A Retinal Organoids
We generated retinal organoids from a patient with USH3A and performed single‐cell RNA sequencing. CLRN1 was specifically expressed in Müller cells, where its variants led to mitochondrial dysfunction and photoreceptor degeneration. ABSTRACT Background Usher syndrome 3A (USH3A), caused by mutations in the CLRN1 gene, leads to retinitis pigmentosa and ...
Rui Zhang +19 more
wiley +1 more source
LC-OCT Features of Confluent and Reticulated Papillomatosis of Gougerot-Carteaud Syndrome. [PDF]
Traini DO +5 more
europepmc +1 more source
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie +3 more
wiley +1 more source
Reticulate acropigmentation of Kitamura with café-au-lait macules: a rare case report. [PDF]
Gao B +5 more
europepmc +1 more source
Impacts of N‐glycanase1 (NGLY1) Down Regulation on the Function of Mitochondria
ABSTRACT N‐glycanase 1 (NGLY1) is involved in intracellular misfolded protein degradation, releasing a de‐N‐glycosylated protein and a complete N‐oligosaccharide. Enzymatic defects in NGLY1 may cause NGLY1‐related congenital disorder of deglycosylation (NGLY1‐CDDG). NGLY1 patients exhibit cognition and coordination defects, and the regulatory impact of
Yanwen Chen +10 more
wiley +1 more source

