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Clinical Utility of Reticulocyte Parameters
The reticulocyte count reflects the erythropoietic activity of bone marrow and is thus useful in both diagnosing anemias and monitoring bone marrow response to therapy. Automated flow-cytometric analysis has led to a significant advance in reticulocyte counting, by simultaneously providing additional parameters and indices such as the reticulocyte ...
Carlo Brugnara, Mario Plebani
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Changes to the membrane proteins and rearrangement of the cytoskeleton must occur for a reticulocyte to mature into a red blood cell (RBC). Different mechanisms of reticulocyte maturation have been proposed to reduce the size and volume of the ...
Bruce, Lesley J +3 more
exaly +2 more sources
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Within-Subject Biological Variation of Reticulocytes and Reticulocyte-Derived Parameters
European Journal of Haematology, 1998Abstract: Automation of reticulocyte counting has decreased the analytical imprecision of this parameter. This has made it possible to use the number of reticulocytes and its derived parameters (reticulocyte maturity and reticulocyte cell indices) in new diagnostic and monitoring situations.
Sverre Sandberg
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Background: The role of measurement of reticulocytes and their parameters is growing in sports medicine. The use of reticulocyte counts in protocols for evaluating and screening for the suspected abuse of hormones that stimulate the bone marrow is an ...
Giuseppe Banfi +2 more
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Reference intervals of extended erythrocyte and reticulocyte parameters
Clinical Chemistry and Laboratory Medicine, 2012AbstractOptical analysis of erythrocytes can provide information on the hemoglobin concentration and content of reticulocytes and mature erythrocytes. Such parameters have proven clinical utility in anemia diagnosis and therapy monitoring. For interpretation, reliable reference ranges are needed.
Johannes J M L, Hoffmann +2 more
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International Journal of Laboratory Hematology, 2017
AbstractIntroductionIn this study, analytic performance (imprecision, carryover, time stability) and diagnostic efficiency of Mindray BC‐6800 analyzer to quantify reticulocytes and extended reticulocyte parameters was evaluated. Moreover, reference intervals on adult population were determined.
Mauro Buttarello
exaly +3 more sources
AbstractIntroductionIn this study, analytic performance (imprecision, carryover, time stability) and diagnostic efficiency of Mindray BC‐6800 analyzer to quantify reticulocytes and extended reticulocyte parameters was evaluated. Moreover, reference intervals on adult population were determined.
Mauro Buttarello
exaly +3 more sources
Mean reticulocyte volume: a specific parameter to screen for hereditary spherocytosis
European Journal of Haematology, 2015AbstractThis study assessed the value of mean reticulocyte volume (MRV) for differential diagnosis of hereditary spherocytosis (HS) so as to develop conventional and new specific screen indexes. Subjects in this study were divided into three groups: 53 cases in HS group, 217 cases in hemolytic anemia control group (109 cases of thalassemia (THAL), 56 ...
Yuchan, Xu +6 more
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Reference values for reticulocyte parameters and hypochromic RBC in healthy children
International Journal of Laboratory Hematology, 2015SummaryIntroductionNew erythrocyte and reticulocyte parameters available on modern hematology analyzers have shown to be useful markers in children. However, pediatric method‐specific reference ranges for these indices are sparse. We aim to establish pediatric reference values for reticulocyte parameters and hypochromic red blood cells in healthy ...
C. Teixeira, J. Barbot, M. I. Freitas
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Changes in Erythropoiesis Assessed by Reticulocyte Parameters During Ultralong Distance Running
Clinical Journal of Sport Medicine, 2002To investigate the possibility of early changes in erythropoiesis during prolonged exercise being reflected in reticulocyte parameters.This was a case-control field study of hematological variables in a group of ultramarathon runners competing in a 6-day track race.A 6-day ultramarathon in Colac, Australia.7 male and 1 female experienced ultramarathon ...
Kieran Edward, Fallon, Graeme, Bishop
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Immature reticulocyte fraction as a useful parameter for blood transfusion assessment in anaemia
British Journal of Biomedical Science, 2009During erythropoietic stress (e.g., acute anaemia) the reticulocyte count in peripheral blood normally increases as the bone marrow responds to increased erythropoietin stimulation of erythroid precursors. The efficiency of this process is an indicator of the patient's bone marrow response.
A R, Geldard, D J, Tobin, A, Cuthbert
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