Blood, 2015 Abstract Reticulocytopenia concurrent with AIHA is a potentially life threatening condition. It has been described with involvement of certain allo or auto antibodies (Kell; Ge3; U) and parvovirus B19 infection. The hemolysis, uncompensated by reticulocytosis, may require transfusion of multiple RBC units as a supportive measure.
Maryse St-Louis
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Severe, Refractory Primary Warm Autoimmune Hemolytic Anemia Requiring 90 Erythrocyte Transfusions [PDF]
Annals of Internal Medicine: Clinical CasesA previously healthy 60-year-old man presented to the hospital with a hemoglobin of 3.5 g/dL. He was diagnosed with severe warm autoimmune hemolytic anemia with reticulocytopenia on hospital day 1 that was not responsive to steroids, immune globulin, and
Neeharika Namineni +3 more
doaj +2 more sources
Reticulocytopenia in immune haemolytic anaemia. [PDF]
BMJ: British Medical Journal, 1978 O B Eden
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Unusual Presentation of B-Cell Chronic Lymphocytic Leukemia Accompanied by Pure Red Cell Aplasia: Case Report [PDF]
Case Reports in OncologyIntroduction: Pure red cell aplasia (PRCA) is a rare bone marrow failure characterized by normocytic anemia and severe reticulocytopenia. Case Presentation: We describe the case of a 38-year-old female who presented with severe anemia.
Jane Atallah +5 more
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Pure Red Cell Aplasia as an Isolated Paraneoplastic Manifestation of Thymoma: A Case Report and Literature Review. [PDF]
Clin Case RepABSTRACT Thymomas are epithelial tumors of the anterior mediastinum and are frequently associated with paraneoplastic autoimmune disorders. Pure red cell aplasia (PRCA) is a rare but clinically significant complication, caused by immune‐mediated suppression of erythropoiesis.
Amer H +8 more
europepmc +2 more sources
Case Report: Possible Paroxysmal Nocturnal Hemoglobinuria with Pronounced Pancytopenia, Reticulocytopenia, and without Hemoglobinuria Simulating Aplastic Anemia [PDF]
Blood, 1952 Abstract 1. This paper describes a case of chronic severe anemia with very pronounced neutropenia and thrombocytopenia and a varying degree of reticulocytopenia. Crosby’s modification of the Ham test for paroxysmal nocturnal hemoglobinuria proved to be strongly positive.
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Erythrophagocytosis on bone marrow found in severe autoimmune hemolytic anemia with reticulocytopenia [PDF]
Blood, 2019 Ilyas Şahin +2 more
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The Turkish Journal of Pediatrics, 1999 We present a four-month-old girl with severe hemolytic anemia and reticulocytopenia. This case is the youngest with hemolytic anemia encountered in our hospital. Findings of autoimmune hemolytic anemia were preceded by diphtheria-pertussis-tetanus
L Olcay, A Düzova, F Gümrük
doaj +2 more sources
Transcription Factors GATA1/2 in Hematological Disorders. [PDF]
EJHaemABSTRACT Background GATA1 and GATA2 are zinc‐finger transcription factors essential for normal hematopoiesis. As genetic testing becomes more widely integrated into clinical practice, GATA1/2‐related disorders are increasingly recognized, making it important for clinicians to understand their diagnosis and management.
Karr M, Palmisiano N, Chen X.
europepmc +2 more sources
Decoding immune-driven erythroid failure in pure red cell aplasia. [PDF]
Br J HaematolPure red cell aplasia (PRCA) is increasingly recognised as a T‐cell‐mediated bone marrow failure syndrome, yet its immunogenetic drivers remain poorly defined. In their paper, Yamashita et al. integrate human leucocyte antigen (HLA) typing, T‐cell receptor repertoire analysis and mutational profiling to reveal enriched HLA alleles, signal transducer ...
Spataro F, Desantis V, Solimando AG.
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