Results 11 to 20 of about 1,434 (146)

Hard-To-Treat Idiopathic Refractory Autoimmune Haemolytic Anaemia with Reticulocytopenia [PDF]

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2020
Autoimmune haemolytic anaemia (AIHA) is an uncommon condition characterized by increased destruction of erythrocytes associated with reticulocytosis in the great majority of cases.
Marcelo Aveiro   +4 more
doaj   +2 more sources

Eculizumab as a Treatment for Hyper-Haemolytic and Aplastic Crisis in Sickle Cell Disease [PDF]

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2021
Background: Patients with sickle cell disease can experience various crises including sequestration crisis, haemolytic crisis and aplastic crisis. Due to alloantibody formation, transfusion alloantibodies can cause a haemolytic crisis. Treatment involves
Ishan Patel   +7 more
doaj   +2 more sources

Effective treatment of refractory monoclonal gammopathy‐associated pure red cell aplasia with isatuximab, pomalidomide and dexamethasone

open access: yeseJHaem
Monoclonal gammopathy‐associated pure red cell aplasia (MG‐PRCA) is characterized by the absence or pronounced hypoplasia of erythroid precursors in the bone marrow, causing reticulocytopenia and a normocytic, normochromic anaemia in a patient with a ...
Christian Sebastian Michel   +8 more
doaj   +3 more sources

Aggressive Systemic Mastocytosis in Association with Pure Red Cell Aplasia

open access: yesCase Reports in Hematology, 2018
Aggressive systemic mastocytosis (ASM) is characterized by mast cell accumulation in systemic organs. Though ASM may be associated with other hematological disorders, the association with pure red cell aplasia (PRCA) is rare and has not been reported ...
Dhauna Karam   +3 more
doaj   +2 more sources

A warm antibody mediated acute hemolytic anemia with reticulocytopenia in a four-month-old girl requiring immunosuppressive therapy

open access: yesThe Turkish Journal of Pediatrics, 1999
We present a four-month-old girl with severe hemolytic anemia and reticulocytopenia. This case is the youngest with hemolytic anemia encountered in our hospital. Findings of autoimmune hemolytic anemia were preceded by diphtheria-pertussis-tetanus
L Olcay, A Düzova, F Gümrük
doaj   +1 more source

Transcription Factors GATA1/2 in Hematological Disorders [PDF]

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Background GATA1 and GATA2 are zinc‐finger transcription factors essential for normal hematopoiesis. As genetic testing becomes more widely integrated into clinical practice, GATA1/2‐related disorders are increasingly recognized, making it important for clinicians to understand their diagnosis and management.
Matthew Karr   +2 more
wiley   +2 more sources

Decoding immune‐driven erythroid failure in pure red cell aplasia [PDF]

open access: yesBritish Journal of Haematology, Volume 208, Issue 5, Page 1887-1889, May 2026.
Pure red cell aplasia (PRCA) is increasingly recognised as a T‐cell‐mediated bone marrow failure syndrome, yet its immunogenetic drivers remain poorly defined. In their paper, Yamashita et al. integrate human leucocyte antigen (HLA) typing, T‐cell receptor repertoire analysis and mutational profiling to reveal enriched HLA alleles, signal transducer ...
Federico Spataro   +2 more
wiley   +2 more sources

Use of IV immunoglobulin to treat steroid resistant, immune checkpoint inhibitor‐induced pure red cell aplasia: A case report [PDF]

open access: yeseJHaem
Pure red cell aplasia (PRCA) is characterised by normocytic normochromic anaemia, reticulocytopenia and reduced erythroid precursors in bone marrow. PRCA as an immune‐related adverse event secondary to immune checkpoint inhibitor (ICI) therapy is rare ...
Sam Sherratt‐Mayhew   +1 more
doaj   +2 more sources

A meta‐analysis of toxicities related to hydroxycarbamide dosing strategies

open access: yeseJHaem, 2020
Due to fear of short‐term toxicities, there is nonconsensus of hydroxycarbamide dosing strategy (escalated vs fixed‐dosing methods), which contributes to its suboptimal use.
Joacy G. Mathias   +9 more
doaj   +2 more sources

Pure red cell aplasia in chronic lymphocytic leukemia: Case report and review of literature

open access: yesIraqi Journal of Hematology, 2016
Despite being immune deficient, chronic lymphocytic leukemia (CLL) patients have an increased incidence of autoimmune cytopenias secondary to autoantibody formation.
Hassanain H Al-Charrakh   +1 more
doaj   +2 more sources

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