Results 41 to 50 of about 1,434 (146)

Case Report: Pure Red Cell Aplasia due to Angioimmunoblastic T-Cell Lymphoma

Case Reports in Oncology, 2020
Pure red cell aplasia (PRCA) is a rare bone marrow failure characterized by a progressive normocytic anemia and reticulocytopenia without leukopenia and thrombocytopenia.
Marina Vitorino, Filipa Nunes, Mariana Costa, Beatriz Porteiro, Alexys Reis Borges, João Machado   +5 more
doaj   +1 more source

An Unusual Case of Hyperhemolysis Syndrome and Delayed Hemolytic Transfusion Reaction due to Anti-Jk(a) and Anti-P1 Antibodies

Case Reports in Medicine, 2023
Background. Hyperhemolysis syndrome (HS) is a severe hemolytic transfusion reaction that can cause hemoglobin and hematocrit levels to drop below pretransfusion levels, leading to severe anemia.
Hunter Montgomery, Matthew X. Luo, Steven Baker, Ming Y. Lim   +3 more
doaj   +1 more source

Parvovirus B19 infections in paediatric sickle cell disease patients: Genotype and hydroxyurea treatment influence disease severity

British Journal of Haematology, EarlyView.
Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections between 2023 and 2025, including symptoms, laboratory parameters ...
Matthias Bleeke, Arne Simon, Beate Winkler, Sabine Heine, Anna Eichinger, Ulrich von Both, Meinolf Siepermann, Sonya El Amouri, Arndt Borkhardt, Yvonne Pritschow, Wolfgang Novak, Michael Dworzak, Sarah Goretzki, Clara Held, Karin Beutel, Franziska Gams, Henriette Rudolph, Leila Koscher, Piet E. Beusker, Eckard Hamelmann, Stefan Weichert, Svenja Häuser, Maximilian Mauritz, Malik Aydin, Verena Wiegering, Regine Grosse, Rainer Misgeld, Martina Stiefel, Nicole Töpfner, Uta Falke, Lara Imhof, Laura Tagliaferri, Daniel Ebrahimi‐Fakhari, Andreas Groll, Marion Appel, Nora Naumann‐Bartsch, Michaela Nathrath, Olaf Beck, Solvej Heidtmann, Philipp Tischer, Ulf Schulze‐Sturm, Urs Mücke, Holger Cario   +42 more
wiley   +1 more source

Expert Consensus on the Diagnosis and Monitoring of Paroxysmal Nocturnal Hemoglobinuria (PNH): An Algorithmic Approach in an Era of New Treatments

European Journal of Haematology, EarlyView.
ABSTRACT Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder caused by a defect of glycosylphosphatidyl‐anchored proteins, leading to an uncontrolled complement‐mediated hemolysis. The advent of complement inhibitors in clinical practice radically changed patients' outcomes and survival.
Bruno Fattizzo, Monia Marchetti, Elisa Cannizzo, Arianna Gatti, Massimo Geuna, Anna Paola Iori, Maddalena Raia, Simona Sica, Francesco Buccisano   +8 more
wiley   +1 more source

Effective treatment of refractory acquired pure red blood cell aplasia with eltrombopag and sirolimus: a case report

Therapeutic Advances in Hematology, 2020
Acquired pure red cell aplasia (aPRCA) is a kind of anemia characterized by severe reticulocytopenia and reduced bone marrow erythroblastic cells. For patients who are refractory to the first-line therapy (cyclosporin A with/without glucocorticoids ...
Yuzhou Huang, Xianyong Jiang, Bing Han
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Acute Myocardial Infarction In Sickle Cell Anaemia Associated With Severe Hypoxia

, 2015
A 17 year old boy with sickle cell anaemia presented with acute myocardial infarction associated with severe hypoxia and reticulocytopenia. Ischaemic heart disease is rare in sickle cell anaemia and in this case it is possible that the acute episode of ...
Saad S.T.O., Schelini F.A., Coelho O.B., Arruda V.R., Junqueira O.O.M.D.   +4 more
core   +1 more source

Neutrophilic Erythrophagocytosis and Reticulocytopenia: A Rare Manifestation of Cold Autoimmune Hemolytic Anemia

Turkish Journal of Hematology, 2022
Priyanaka Gupta, Seema Biswas, Manish Singh Singh, Ruchi Gupta   +3 more
doaj   +1 more source

SARS-CoV-2 infection in an infant with non-respiratory manifestations: a case report

Egyptian Pediatric Association Gazette, 2021
Background Coronavirus disease (COVID-19) presents in children usually with less severe manifestations than in adults. Although fever and cough were reported as the most common symptoms, children can have non-specific symptoms. We describe an infant with
Muhammad Adel, Ahmed Magdy
doaj   +1 more source

Hemophagocytic Lymphohistiocytosis Triggered by Legionella pneumophila and SARS‐CoV‐2 Infection in GATA2 Deficiency

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Germline GATA2 deficiency predisposes to bone marrow failure, myeloid neoplasia, and immune dysregulation. The syndrome is often complicated by infection with intracellular pathogens and viruses, autoimmunity, and inflammation. Hemophagocytic lymphohistiocytosis (HLH) is a rare occurrence that can present further management challenges.
Harry Wilson, Nuno Borges, Matthew Collin, Callum Wright   +3 more
wiley   +1 more source