Results 91 to 100 of about 698,339 (387)

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Loss-of-function analysis of EphA receptors in retinotectal mapping [PDF]

, 2004
Peer reviewedPublisher ...
DeChiara, Thomas M., Feldheim, David A., Flanagan, John G., Gale, Nicholas W., Nakamoto, Masaru, Osterfield, Miriam, Rohatgi, Rajat, Yancopoulos, George D.   +7 more
core   +1 more source

Comparative analysis of pre-operative findings and post-operative outcomes in primary and secondary macular holes at a tertiary eye hospital in South India

International Journal of Retina and Vitreous
Purpose This study aimed to compare demographics, clinical characteristics, and post-surgical outcomes between idiopathic and secondary full-thickness macular holes (MHs).
Shubham Darade, Rupal Kathare, Ayushi Choudhary, Gaurang Sehgal, Jay Chhablani, Kanika Godani, Naresh Kumar Yadav, Priyanka Gandhi, Prathiba Hande, Rubble Mangla, Vishma Prabhu, Ramesh Venkatesh   +11 more
doaj   +1 more source

Treat and extend regimen with aflibercept for chronic central retinal vein occlusions: 2 year results of the NEWTON study

International Journal of Retina and Vitreous, 2019
Background To determine whether aflibercept (Eylea; Regeneron Pharmaceuticals, Inc., Tarrytown, NY) could continue to extend the macular edema free interval in patients on a treat and extend (TAE) with non-ischemic central retinal vein occlusions (CRVOs)
Rahul N. Khurana, Louis K. Chang, Alok S. Bansal, James D. Palmer, Chengqing Wu, Mark R. Wieland   +5 more
doaj   +1 more source

Space-time wiring specificity supports direction selectivity in the retina

Nature, 2014
How does the mammalian retina detect motion? This classic problem in visual neuroscience has remained unsolved for 50 years. In search of clues, here we reconstruct Off-type starburst amacrine cells (SACs) and bipolar cells (BCs) in serial electron ...
Jinseop S. Kim, M. Greene, A. Zlateski, Kisuk Lee, Mark Richardson, Srinivas C. Turaga, Michael J. Purcaro, Matthew Balkam, A. Robinson, Bardia F. Behabadi, M. Campos, W. Denk, H. Seung   +12 more
semanticscholar   +1 more source

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

Advanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño, Carlos Bendicho‐Lavilla, Haya Alfassam, Bárbara Blanco‐Fernández, Abdul W. Basit, Francisco J. Otero‐Espinar   +5 more
wiley   +1 more source

Retinal adaptation of Japanese common squid (Todarodes pacificus Steenstrup) to light changes [PDF]

, 1985
The response of retinae of the Japanese common squid (Todarodes pacificus Steenstrup) was recorded in relation to various light intensities. In the light-adapted eye of common squid, the black pigment ascends to the external limiting membrance of the ...
Hiroshi, Inada, Hiroya, Takahashi, Tsuneyoshi, Suzuki   +2 more
core  

A Novel Reporter Mouse Uncovers Endogenous Brn3b Expression. [PDF]

, 2019
Brn3b (Pou4f2) is a class-4 POU domain transcription factor known to play central roles in the development of different neuronal populations of the Central Nervous System, including retinal ganglion cells (RGCs), the neurons that connect the retina with ...
Cheema, Simranjeet K, La Torre, Anna, Mercado-Ayon, Yesica, Miltner, Adam M, Zawadzki, Robert J, Zhang, Pengfei   +5 more
core   +1 more source

Coats-Like reaction post-vitreoretinal surgery for PDR managed with laser photocoagulation and adjunctive intravitreal steroids– a case report

BMC Ophthalmology
Purpose To report a rare case of a Coats-like response developing after vitreoretinal surgery for proliferative diabetic retinopathy (PDR) and its successful management with retinal laser photocoagulation and adjunctive intravitreal steroids.
Kanika Godani, Shruti Vidyasagar, Preksha Biradar, Vishma Prabhu, Prathiba Hande, Priyanka Gandhi, Rupal Kathare, Jay Chhablani, Ramesh Venkatesh   +8 more
doaj   +1 more source

Polymer‐Incorporated Mechanically Compliant Carbon Nanotube Microelectrode Arrays for Multichannel Neural Signal Recording

Advanced Functional Materials, EarlyView.
This work presents a soft microelectrode array based on vertically aligned carbon nanotube (CNT) forests, combining high conductivity with mechanical softness. A densification process and air‐pressure‐assisted flexibilization improve structural integrity, ensuring stable insertion and reduced inflammation.
Hyeonhee Roh, Kwangjun Kim, Chaesung Kim, Minju Kim, Minwook Kim, Sangjun Sim, Jongbaeg Kim, Jong G. Ok, Maesoon Im   +8 more
wiley   +1 more source