Results 81 to 90 of about 522,726 (295)

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Early Outcomes of Intravitreal Aflibercept 8 mg in Eyes Previously Treated with Aflibercept 2 mg for Neovascular Age-Related Macular Degeneration with AI-Based Biomarker Quantification

Ophthalmology and Therapy
Introduction To evaluate the early outcomes of aflibercept 8 mg (afl8) treatment in patients with neovascular age-related macular degeneration (nAMD) previously treated with aflibercept 2 mg (afl2).
Nicolò Bartolomeo, Konstantinos Kitsos Kalyvianakis, Yannic Pannatier Schuetz, Anna Chiara Nascimbeni, Daniela Gallo Castro, Baptiste Crozat, Mamadou Pathé Barry, Aude Ambresin   +7 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Intravitreal faricimab in patients with refractory diabetic macular edema: 6-month fluid analysis using artificial intelligence

BMC Ophthalmology
Purpose Diabetic macular edema (DME) is a leading cause of vision loss in patients with diabetes. In developed countries, intravitreal (IVT) anti-vascular endothelial growth factor (VEGF) injections are the standard-of-care first-line treatment for DME ...
Nicolas Owlya, Mickael Barbosa, Nicolò Bartolomeo, Yannic Pannatier-Schuetz, Anna Chiara Nascimbeni, Daniela Gallo Castro, Mamadou Pathé Barry, Aude Ambresin   +7 more
doaj   +1 more source

Efficient Egocentric Visual Perception Combining Eye-tracking, a Software Retina and Deep Learning [PDF]

, 2018
We present ongoing work to harness biological approaches to achieving highly efficient egocentric perception by combining the space-variant imaging architecture of the mammalian retina with Deep Learning methods.
Hristozova, Nina, Ozimek, Piotr, Siebert, Jan Paul   +2 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Can Laser Retinopexy Prevent Retinal Detachment in Asymptomatic, High-Risk Eyes?

Clinical Ophthalmology
Robert E Morris,1– 3 Mathew R Sapp,1– 3 Dewayne R Conn,1,2 Harshvardhan Chawla,1– 3 Ferenc Kuhn1,4 1Helen Keller Eye Research Foundation, Birmingham, AL, USA; 2Retina Specialists of Alabama, Birmingham, AL, USA; 3Department of Ophthalmology, University ...
Morris RE, Sapp MR, Conn DR, Chawla H, Kuhn F   +4 more
doaj  

Coats-Like reaction post-vitreoretinal surgery for PDR managed with laser photocoagulation and adjunctive intravitreal steroids– a case report

BMC Ophthalmology
Purpose To report a rare case of a Coats-like response developing after vitreoretinal surgery for proliferative diabetic retinopathy (PDR) and its successful management with retinal laser photocoagulation and adjunctive intravitreal steroids.
Kanika Godani, Shruti Vidyasagar, Preksha Biradar, Vishma Prabhu, Prathiba Hande, Priyanka Gandhi, Rupal Kathare, Jay Chhablani, Ramesh Venkatesh   +8 more
doaj   +1 more source

Macular Hole Progression after Intravitreal Bevacizumab for Hemicentral Retinal Vein Occlusion

Case Reports in Ophthalmological Medicine, 2011
Macular edema secondary to retinal vein occlusion is commonly being treated with off-label intravitreal bevacizumab with good outcomes. A significant reduction in macular edema and improvement in visual acuity is seen following such a treatment with no ...
Manish Nagpal, Vikram Mehta, Kamal Nagpal   +2 more
doaj   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source