Results 61 to 70 of about 537,300 (352)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

On the AER Stereo-Vision Processing: A Spike Approach to Epipolar Matching [PDF]

, 2013
Image processing in digital computer systems usually considers visual information as a sequence of frames. These frames are from cameras that capture reality for a short period of time.
Cerezuela Escudero, Elena, Domínguez Morales, Manuel Jesús, Jiménez Fernández, Ángel Francisco, Jiménez Moreno, Gabriel, Linares Barranco, Alejandro, Pérez Peña, Fernando   +5 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Methylene blue associated retinal toxicity

International Journal of Retina and Vitreous
Background To describe a case of inadvertent methylene blue use during pars plana vitrectomy (PPV) for an epiretinal membrane (ERM). Case A 69-year-old man presented with 1 day of severe vision loss in his left eye. Two days prior to presentation, he had
Sidra Zafar, Martin Calotti, Timothy T. Xu, Justin Muste, Theodore Bowe, Luis Acaba-Berrocal, Brian Cheng, Samir N. Patel, Yoshihiro Yonekawa, Jose S. Pulido, Jordan D. Deaner   +10 more
doaj   +1 more source

Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]

, 2015
Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco, BATTAGLIONE, Ezio, BIANCHI, ENRICA, Feher, Janos, Kovacs, Illes, MAGLIULO, Giuseppe, Micera, Alessandra, ORLANDO, Maria Patrizia, PLATEROTI, Rocco, Ripandelli, Guido, TAURONE, SAMANTA   +10 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Central retinal vein occlusion after laparoscopic sleeve gastrectomy in an 18-year-Old female

American Journal of Ophthalmology Case Reports, 2021
Purpose: To describe a case of central retinal vein occlusion (CRVO) in a young adult found to have elevated homocysteine after bariatric surgery and to review risk factors for CRVO in younger patients.
Michael J. Ammar, Connie M. Wu, Matthew R. Starr, Carl D. Regillo   +3 more
doaj   +1 more source

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

Neuron, 2017
SUMMARY In the developing retina, multipotent neural progenitors undergo unidirectional differentiation in a precise spatiotemporal order. Here we profile the epigenetic and transcriptional changes that occur during retinogenesis in mice and humans ...
Issam Aldiri, Beisi Xu, Lu Wang, Xiang Chen, Daniel J. Hiler, Lyra M. Griffiths, Marcus L Valentine, A. Shirinifard, Suresh Thiagarajan, A. Sablauer, Marie E. Barabas, Jiakun Zhang, Dianna A. Johnson, S. Frase, Xin Zhou, J. Easton, Jinghui Zhang, E. Mardis, R. Wilson, J. Downing, M. Dyer   +20 more
semanticscholar   +1 more source

Irregular S-cone mosaics in felid retinas: spatial interaction with axonless horizontal revealed by cross-correlation [PDF]

, 2000
In most mammals short-wavelength-sensitive (S) cones are arranged in irregular patterns with widely variable intercell distances. Consequently, mosaics of connected interneurons either may show some type of correlation to photoreceptor placement or may ...
Ahnelt, Ahnelt, Ahnelt, Ahnelt, Ahnelt, Anna Kübber-Heiss, Boycott, Chan, Chiu, Clark, Cook, Curcio, Curcio, Dacey, de Monasterio, Eduardo Fernández, Famiglietti, Fernández, Gallego, Galli-Resta, Green, Hack, Hendrickson, Hokoç, Johnson, Jose Angel Bolea, Kolb, Kouyama, Long, Luo, Martin, Mills, Müller, Oscar Martinez, Peter Kurt Ahnelt, Pflug, Provencio, Raviola, Rodieck, Rodieck, Sandmann, Shapiro, Soni, Sun, Szél, Szél, Szél, Wikler, Williams, Williams, Wässle, Wässle, Wässle   +52 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source