Results 131 to 140 of about 409,228 (346)
Advanced Science, EarlyView.D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei +18 more
wiley +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
Review of Beitrag zur Lehre des intermittierenden Lichtreizes der gesunden und der kranken Retina. [PDF]
, 1905 C. Homer Bean
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Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
Advanced Science, EarlyView.In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao +12 more
wiley +1 more source
Ueber die geometrische Gestalt der theoretischen Retina des periskopischen schematischen Auges [PDF]
, 1879 Ludwig Matthiessen
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Advanced Science, EarlyView.A novel multiple cross‐linked betaine‐type amphiphilic polymer hydrogels are developed via in situ free radical copolymerization. The resultant formation, named P(SBMA‐co‐AANa) hydrogel, functions as a vitreous substitute and demonstrates superior performance in optical properties, support capacity, and biocompatibility on a vitrectomized rabbit model.
Yuting Cai +8 more
wiley +1 more source
A Peculiar Lamellated Body Observed in the Cells of the Pigment Epithelium of the Retina of the Bat, Pipistrellus abramus [PDF]
, 1958 Eichi Yamada
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Artificial intelligence in retina
Progress in retinal and eye research, 2018 U. Schmidt-Erfurth +4 more
semanticscholar +1 more source