Results 121 to 130 of about 315,719 (318)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Multifaceted approach to evacuating multi-level premacular hemorrhage in a case of suspected Valsalva retinopathy – a case report

BMC Ophthalmology
Background Accurate localization of premacular hemorrhages (PMHs) is crucial as treatment strategies vary significantly based on whether the hemorrhage resides within the vitreous gel, subhyaloid space, or beneath the internal limiting membrane (ILM ...
B. R. Smitha, Naman Sahni, Priyanka Gandhi, Rupal Kathare, Vishma Prabhu, Prathiba Hande, Jay Chhablani, Ramesh Venkatesh   +7 more
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Smoke-stack fluorescein leakage in a vitrectomised eye with proliferative diabetic retinopathy: a rare angiographic phenomenon

BMC Ophthalmology
Background/Aim This case report aims to describe an unusual angiographic finding of smoke-stack leakage (SSL) in a vitrectomised eye of a patient with proliferative diabetic retinopathy (PDR). Case description A 59-year-old male with a 17-year history of
Kanika Godani, Vishma Prabhu, Prathiba Hande, Priyanka Gandhi, Rupal Kathare, Ramesh Venkatesh   +5 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

THE ROLE OF TYROSINASE IN THE TIME COURSE OF LIGHT-INDUCED CONE MOVEMENTS IN GOLDFISH RETINA [PDF]

, 2016
Many teleosts regulate the amount of light incident to the retina through retinomotor movements (RMMs), adjustments of the length of photoreceptors and the distribution of melanin within retinal pigment epithelium (RPE).
Thapa, Sophie
core  

Quantitative Assessment of En‑face OCT‑Derived Minimum Intensity Fluid Changes Following Ranibizumab Biosimilar Therapy in Macular Neovascularization Secondary to nAMD and PCV

Clinical Ophthalmology
Jay Umed Sheth,1 Ankit Kumar Bhopalka,2 Bhagyashree Meshram,1 Sayali Karande1 1Department of Retina Services, Shantilal Shanghvi Eye Institute, Mumbai, India; 2Department of Retina Services, Katihar Satyabhama Netralaya, Katihar, IndiaCorrespondence: Jay
Sheth JU, Bhopalka AK, Meshram B, Karande S   +3 more
doaj  

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Gyrate atrophy of the choroid and retina [PDF]

, 2013
Retina ve koroidin gyrate atrofisi otozomal resesif geçişli midperiferal retinada birbirinden ayrışık koryoretinal atrofi alanları ile karakterize yavaş ilerleyici bir koryoretinal distrofidir. Bu distrofi ornitin aminotransferaz eksikliği sonucu hiperor-
Keskin, Uğurcan, Öksüz, Hüseyin, Ayıntap, Emre, Ayhan Tuzcu, Esra, Nilüfer, İlhan, Dağlıoğlu, Mutlu, İlhan, Özgür   +6 more
core  

Cystoid macular oedema after flanged intraocular lens scleral fixation using the Yamane technique: a multicentre cohort study

Scientific Reports
This retrospective observational multicentre cohort study compared the rate of postoperative cystoid macular oedema (CME) between two intraocular lens (IOL) scleral fixation (SFIOL) techniques: a flanged IOL fixation technique (Yamane technique) and a ...
Hiroto Ishikawa, Kazutaka Uchida, Hiroto Terasaki, Taiji Sakamoto, Masashi Kakinoki, Masahito Ohji, Tatsuya Jujo, Hitoshi Takagi, Yoshinori Mitamura, Yutaka Yamada, Yoshihiro Takamura, Masahiko Sugimoto, Mineo Kondo, Shigeo Yoshida, Hisashi Fukuyama, Fumi Gomi   +15 more
doaj   +1 more source