Results 11 to 20 of about 726,050 (386)
bioRxiv, 2017 Here we report multiple lines of evidence for a comprehensive model for retinal energy metabolism. Metabolic flux, locations of key enzymes and our finding that glucose enters the neural retina almost entirely through photoreceptors support a ...
Mark A Kanow +16 more
openalex +2 more sources
The blood–retina barrier in health and disease
The FEBS Journal, 2021 The blood–retina barrier (BRB) is the term used to define the properties of the retinal capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation from the retina. More specifically, the inner blood–retina barrier (iBRB)
Fionn O'Leary, M. Campbell
semanticscholar +1 more source
Retina Metabolism and Metabolism in the Pigmented Epithelium: A Busy Intersection.
Annual Review of Vision Science, 2021 The outer retina is nourished from the choroid, a capillary bed just inside the sclera. O2, glucose, and other nutrients diffuse out of the choroid and then filter through a monolayer of retinal pigment epithelium (RPE) cells to fuel the retina.
J. Hurley
semanticscholar +1 more source
Identification of early pericyte loss and vascular amyloidosis in Alzheimer’s disease retina
Acta Neuropathologica, 2020 Pericyte loss and deficient vascular platelet-derived growth factor receptor-β (PDGFRβ) signaling are prominent features of the blood–brain barrier breakdown described in Alzheimer’s disease (AD) that can predict cognitive decline yet have never been ...
Haoshen Shi +15 more
semanticscholar +1 more source
Central posterior hyaloid fibrosis: evolution and outcomes
International Journal of Retina and Vitreous, 2023 Purpose To report contributory factors and clinical outcomes of central posterior hyaloid fibrosis (CPHF) associated with neovascular age-related macular degeneration (nAMD). Methods In this retrospective, single-center study, patients with CPHF and nAMD
Ramesh Venkatesh +8 more
doaj +1 more source
Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]
, 2019 As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick +2 more
core +1 more source
Progress in Retinal and Eye Research, 2012 Ciliary neurotrophic factor (CNTF) is one of the most studied neurotrophic factors for neuroprotection of the retina. A large body of evidence demonstrates that CNTF promotes rod photoreceptor survival in almost all animal models. Recent studies indicate that CNTF also promotes cone photoreceptor survival and cone outer segment regeneration in the ...
Rong, Wen +3 more
openaire +2 more sources
2012 IEEE Conference on Computer Vision and Pattern Recognition, 2012 A large number of vision applications rely on matching keypoints across images. The last decade featured an arms-race towards faster and more robust keypoints and association algorithms: Scale Invariant Feature Transform (SIFT)[17], Speed-up Robust ...
Alexandre Alahi +2 more
semanticscholar +1 more source
Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
, 2012 Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong +5 more
core +2 more sources
Neural ensemble decoding reveals a correlate of viewer- to object-centered spatial transformation in monkey parietal cortex [PDF]
, 2008 The parietal cortex contains representations of space in multiple coordinate systems including retina-, head-, body-, and world-based systems. Previously, we found that when monkeys are required to perform spatial computations on objects, many neurons in
Averbeck, BB, Chafee, MV, Crowe, DA
core +1 more source