Results 31 to 40 of about 637,330 (312)
A single‐cell transcriptome atlas of the adult human retina
EMBO Journal, 2019 The retina is a specialized neural tissue that senses light and initiates image processing. Although the functional organization of specific retina cells has been well studied, the molecular profile of many cell types remains unclear in humans.
S. Lukowski +22 more
semanticscholar +1 more source
Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]
, 2013 BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A +5 more
core +6 more sources
International Journal of Retina and Vitreous, 2023 Purpose To compare real-life data on delayed intravitreal treatment of diabetic macular edema (DME) patients to early treatment. Methods In this single-centre, retrospective, interventional, comparative study, DME patients were divided into two groups ...
Sai Prashanti Chitturi +6 more
doaj +1 more source
Neural ensemble decoding reveals a correlate of viewer- to object-centered spatial transformation in monkey parietal cortex [PDF]
, 2008 The parietal cortex contains representations of space in multiple coordinate systems including retina-, head-, body-, and world-based systems. Previously, we found that when monkeys are required to perform spatial computations on objects, many neurons in
Averbeck, BB, Chafee, MV, Crowe, DA
core +1 more source
Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
, 2012 Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong +5 more
core +2 more sources
Microglia in the Retina: Roles in Development, Maturity, and Disease.
Annual Review of Vision Science, 2018 Microglia, the primary resident immune cell type, constitute a key population of glia in the retina. Recent evidence indicates that microglia play significant functional roles in the retina at different life stages.
Sean M. Silverman, W. Wong
semanticscholar +1 more source
Vitrectomy Due to Vitreous Hemorrhage and Tractional Retinal Detachment Secondary to Eales’ Disease
Türk Oftalmoloji Dergisi, 2021 Objectives:To investigate visual and anatomical outcomes of vitreoretinal surgeries in patients with Eales’ disease.Materials and Methods:In this retrospective study, 22 eyes of 21 patients with vitreous hemorrhage (VH) or tractional retinal detachment ...
M. Giray Ersöz +4 more
doaj +1 more source
Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma.
JAMA ophthalmology, 2015 IMPORTANCE Vascular factors may have important roles in the pathophysiology of glaucoma. A practical method for the clinical evaluation of ocular perfusion is needed to improve glaucoma management. OBJECTIVE To detect peripapillary retinal perfusion in
Liang Liu +8 more
semanticscholar +1 more source
Sphingolipids as emerging mediators in retina degeneration [PDF]
, 2019 The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber +3 more
core +1 more source
bioRxiv, 2017 Here we report multiple lines of evidence for a comprehensive model for retinal energy metabolism. Metabolic flux, locations of key enzymes and our finding that glucose enters the neural retina almost entirely through photoreceptors support a ...
Mark A. Kanow +16 more
semanticscholar +1 more source