Results 131 to 140 of about 448,957 (296)
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Advanced Science, EarlyView.This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren +11 more
wiley +1 more source
FREE AMINO ACIDS IN THE CHOROID AND EFFECTS OF SOME METABOLITES ON THE RETINAL PIGMENT MIGRATION
, 1959 Isao Hanawa, Sigeo Tanaka, Hideo Nakano
openalex +2 more sources
RETINAL MICRO-ANEURYSMS AND PUNCTATE HAEMORRHAGES [PDF]
, 1944 A. J. Ballantyne, Arnold Loewenstein
openalex +1 more source
Advanced Science, EarlyView.Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li +11 more
wiley +1 more source
Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening
Advanced Science, EarlyView.Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin +6 more
wiley +1 more source
The spectral sensitivity of the pigeon's retinal elements
, 1953 K. O. Donner
openalex +2 more sources
Injection of the Retinal Vascular System in the Enucleated Eye in Diabetic Retinopathy [PDF]
, 1950 Nicholas J. Ashton
openalex +1 more source
Advanced Science, EarlyView.Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua +15 more
wiley +1 more source