Results 121 to 130 of about 719,139 (306)
The PRIS-Tool. Preparing for clinical studies
Current Directions in Biomedical EngineeringThe entoptic view of the retina is a fascinating phenomenon that is caused by light stimulation. Over the course of the past two years, we have been developing our Purkinje Retinal Image Stabilizer (PRIS) method to simplify entoptic testing for retinal ...
Tautorat Carsten +6 more
doaj +1 more source
BiomoleculesInherited macular dystrophies (iMDs) are a group of genetic disorders, which affect the central region of the retina. To investigate the genetic basis of iMDs, we used single-molecule Molecular Inversion Probes to sequence 105 maculopathy-associated ...
Rebekkah J. Hitti-Malin +59 more
doaj +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Diabetes Alters Diurnal Rhythm of Electroretinogram in db/db Mice [PDF]
, 2019 Diabetic retinopathy (DR) is the most common complications of diabetes and a leading cause of blindness in the United States. The retinal neuronal changes precede the vascular dysfunction observed in DR.
Bhatwadekara, Ashay D. +3 more
core
Advanced Science, EarlyView.Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source
Role of P2X7R in Retinal Diseases: A Review
Immunity, Inflammation and DiseaseBackground P2X purinoceptor 7 receptor (P2X7R) is an ATP‐gated ion channel that, upon activation by ATP, triggers the release of inflammatory mediators and induces apoptosis in cells.
Chunli Li, Binsheng Wang
doaj +1 more source
Establishing death in stranded Odontocetes (toothed whales) using other mammals : a pilot study : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Zoology at Massey University [PDF]
, 2003 The aim of this study was to investigate and evaluate a new method for determining death in stranded odontocetes (toothed whales). The new method was using the pulsations seen in the retinal blood vessels in the place of the heart rate. The retinal blood
Paul, Katherine A
core
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices
Advanced Science, EarlyView.This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee +4 more
wiley +1 more source
Applied SciencesFollowing the significant advancement in the cosmetic field over the past few decades, carotenoids, vitamin A, and vitaminoids have emerged as pivotal components in the formulation of cosmetic products due to their diverse bioactive properties.
Theodora Adamantidi +5 more
doaj +1 more source