Results 151 to 160 of about 1,135,598 (287)

The cell biology of the retinal pigment epithelium

Progress in retinal and eye research, 2020
Aparna Lakkaraju, Ankita Umapathy, L. Tan, Lauren L Daniele, N. Philp, K. Boesze-Battaglia, David S. Williams   +6 more
semanticscholar   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Amyloid-β-induced pyroptosis drives retinal neurodegeneration in a TgAPPswePS1 mouse model. [PDF]

Int J Ophthalmol
Cao JR, Li J, Zheng HH, Dong ZZ.
europepmc   +1 more source

Pathogenicity of Mediator Complex Subunit 27 (MED27) in a Neurodevelopmental Disorder with Cerebellar Atrophy

Advanced Science, EarlyView.
MED27 is one of the 26 subunits in the human Mediator complex (MED). Neurodevelopmental disorder‐causing MED27 genetic variants induce instability of MED, leading to disrupted DNA occupancy, altered chromatin interaction, and subsequent transcriptional dysregulation of critical downstream genes, including master regulatory transcription factors ...
Nuermila Yiliyaer, Xiaocheng Li, Tianyu Guo, Haiying Zhou, Lihai Gong, Luowei Yuan, Yang Fu, Yulong Qiao, Ying Lam Lui, Nuo Chen, Pengfei Lin, Hoi Hung Cheung, Ho Ko, Linyan Meng, Xiao Chen, Yong Lei, Kin Ming Kwan, Huating Wang, Shen Gu   +18 more
wiley   +1 more source

Hemoglobin oxygen saturation in myopic eyes: a scanning laser ophthalmoscope study. [PDF]

Int J Ophthalmol
Xiao ZX, Qiu KL, Zhou H, Zheng DZ, Ng TK, Wang G.   +5 more
europepmc   +1 more source

Retinal cavitations in macular telangiectasia type 2 (MacTel): longitudinal structure–function correlations

, 2020
Cindy X. Cai, John Choong, Sina Farsiu, Stephanie J. Chiu, Emily Y. Chew, Glenn J. Jaffe   +5 more
openalex   +2 more sources

Amplitude Modulation-based Electrical Stimulation for Encoding Multipixel Spatiotemporal Visual Information in Retinal Neural Activities [PDF]

, 2017
Sang Baek Ryu, Jeong Woo Choi, Kun No Ahn, Yong Sook Goo, Kyung Hwan Kim   +4 more
openalex   +1 more source

Pharmacokinetic aspects of retinal drug delivery

Progress in retinal and eye research, 2017
E. D. Amo, A. Rimpelä, Emma M. Heikkinen, Otto K. Kari, Eva Ramsay, Tatu Lajunen, M. Schmitt, Laura Pelkonen, Madhushree Bhattacharya, D. Richardson, A. Subrizi, T. Turunen, M. Reinisalo, Jaakko Itkonen, Elisa Toropainen, Marco G. Casteleijn, H. Kidron, M. Antopolsky, Kati-Sisko Vellonen, Marika Ruponen, A. Urtti   +20 more
semanticscholar   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Expression of Neurotrophin-3 (NT-3) and Anterograde Axonal Transport of Endogenous NT-3 by Retinal Ganglion Cells in Chick Embryos [PDF]

, 2000
Christopher S. von Bartheld, Rafał Butowt   +1 more
openalex   +1 more source