Autoantibodies against retinal proteins in paraneoplastic and autoimmune retinopathy [PDF]
BACKGROUND: Autoimmune retinal degeneration may occur in patients who present with sudden or, less commonly, subacute loss of vision of retinal origin, associated with an abnormal ERG, through the action of autoantibodies against retinal proteins.
AH Milam+31 more
core +3 more sources
Uptake and metabolism of retinol (vitamin A) in the isolated perfused rat liver
The isolated perfused liver was employed to study various aspects of retinol-C14 metabolism. The rate of uptake of retinol, retinal, retinoic acid, and retinol acetate was rapid (first-order rate constant, k = 0.12–0.16 min−1) during the first 3–10 min ...
Richard D. Zachman, James Allen Olson
doaj
A Dark and Bright Channel Prior Guided Deep Network for Retinal Image Quality Assessment [PDF]
Retinal image quality assessment is an essential task in the diagnosis of retinal diseases. Recently, there are emerging deep models to grade quality of retinal images. Current state-of-the-arts either directly transfer classification networks originally designed for natural images to quality classification of retinal images or introduce extra image ...
arxiv
Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]
BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A+5 more
core +2 more sources
Free Radical Mediated Oxidative Degradation of Carotenes and Xanthophylls
This article reviews the excited-state quenching, pro-vitamin A activity and anticarcinogenicity of carotenes and xanthophylls in relation to their chemical structures.
Raphael C. Mordi+4 more
doaj +1 more source
Retinal Vessel Segmentation Using A New Topological Method [PDF]
A novel topological segmentation of retinal images represents blood vessels as connected regions in the continuous image plane, having shape-related analytic and geometric properties. This paper presents topological segmentation results from the DRIVE retinal image database.
arxiv
Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]
Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco+10 more
core +1 more source
The Effect of Cone Opsin Mutations on Retinal Structure and the Integrity of the Photoreceptor Mosaic [PDF]
Purpose. To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations. Methods. Eleven subjects were recruited, eight of whom have been previously described.
Banin, Eyal+19 more
core +2 more sources
Müller cell activation, proliferation and migration following laser injury. [PDF]
PurposeMüller cells are well known for their critical role in normal retinal structure and function, but their reaction to retinal injury and subsequent role in retinal remodeling is less well characterized. In this study we used a mouse model of retinal
Flannery, John G+8 more
core +2 more sources
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids [PDF]
Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for directing stem cell renewal and differentiation.
Al-Aama, Jumana+15 more
core +2 more sources