Results 81 to 90 of about 1,135,598 (287)
Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications
Advanced Healthcare Materials, EarlyView.This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin +6 more
wiley +1 more source
A Unified Model of Spatiotemporal Processing in the Retina [PDF]
, 1992 A computational model of visual processing in the vertebrate retina provides a unified explanation of a range of data previously treated by disparate models.
Gaudiano, Paolo
core +1 more source
Investigative Ophthalmology and Visual Science, 2017 Purpose To compare optical coherence tomography (OCT) angiographic parameters in retina and choriocapillaris between control subjects and diabetic patients without diabetic retinopathy (NDR).
G. Dimitrova +4 more
semanticscholar +1 more source
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research
Advanced Healthcare Materials, EarlyView.Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter +5 more
wiley +1 more source
Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Rods and cones are photoreceptor cells with different distributions and functions in the human retina. Rods are dominant at the periphery, which is responsible for peripheral vision; cones are enriched in the macula, which is responsible for
Sangbae Kim +14 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk +6 more
wiley +1 more source
bioRxiv, 2017 Here we report multiple lines of evidence for a comprehensive model for retinal energy metabolism. Metabolic flux, locations of key enzymes and our finding that glucose enters the neural retina almost entirely through photoreceptors support a ...
Mark A. Kanow +16 more
semanticscholar +1 more source
3D Printing Strategies for Bioengineering Human Cornea
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan +4 more
wiley +1 more source
Visual pigment bleaching in isolated salamander retinal cones. Microspectrophotometry and light adaptation. [PDF]
, 1993 G J Jones +3 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer +17 more
wiley +1 more source