Results 161 to 170 of about 1,720,622 (330)
Small Methods, EarlyView.This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source
Interventional oncology in children: Where are we now?
Journal of Medical Imaging and Radiation Oncology, EarlyView.Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel +1 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Development of a Swine Whole Eye Transplant Ex Vivo Perfusion Protocol
Artificial Organs, EarlyView.This study establishes the first subnormothermic machine perfusion protocol for whole eye transplants in a swine model, enabling up to 18 h of preservation with stable metabolic function, limited edema, and recovery of mydriasis. ABSTRACT Background The first human Whole Eye Transplant (WET) has sparked new hope for patients who have lost vision due to
Haïzam Oubari +8 more
wiley +1 more source
Exploring the effect of gestational diabetes mellitus on retinal vascular morphology by PKSEA-Net
Frontiers in Cell and Developmental BiologyBackgroundGestational diabetes mellitus (GDM) is a temporary metabolic disorder in which small retinal vessels may have experience subtle changes before clinical lesions of the fundus retina appear.
Ligang Jiang +6 more
doaj +1 more source
Retinal oximetry in central retinal artery occlusion [PDF]
Acta Ophthalmologica, 2012 Sveinn H, Hardarson +3 more
openaire +2 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To evaluate the incidence, outcomes, and risk factors of numerical hypotony (NH) and choroidal effusion (CE) following standalone PRESERFLO MicroShunt (PMS) implantation. Methods Primary open‐angle glaucoma (POAG) and pseudoexfoliative glaucoma (PXG) patients with uni‐ or bilateral surgery at a tertiary university hospital were ...
Emil Nasyrov +5 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To compare retinal vessel oxygen saturations and diameters before, 1 and 3 months after trabeculectomy. Methods Retinal oxygen saturations and vessel diameters were obtained using retinal oximetry. The effect of the postoperative intraocular pressure (IOP) decrease on the arteriovenous difference (AV‐difference) was evaluated ...
S. Kemp +5 more
wiley +1 more source