Results 141 to 150 of about 10,917,188 (341)

Perfluorodecalin and Viscoelastic-Assisted Internal Limiting Membrane Flap Technique for High Myopia Macular Hole Retinal Detachment

Clinical Ophthalmology
Junwen He,1 Li Yan,1 Shan Wang2 1Department of Retinal & Vitreous Diseases, Aier Eye Hospital of Wuhan University, Wuhan, People’s Republic of China; 2Department of Ophthalmic Imaging, Aier Eye Hospital of Wuhan University, Wuhan, People’s Republic ...
He J, Yan L, Wang S
doaj  

Risk Factors for Focal Choroidal Excavation Concurrent with Chorioretinal Disease: Evaluated by Spectral-Domain OCT

Ophthalmology Science
Purpose: To investigate the risk factors for patients with focal choroidal excavation (FCE) and their correlation with chorioretinal diseases. Design: Retrospective cross-sectional study.
Yiwen Ou, MD, Minghui Qiu, MD, Mengyuan Li, MD, Yajun Mi, BS, Dezheng Wu, MD, PhD, Shibo Tang, MD, PhD, Weiwei Dai, MD, PhD, Jacey Hongjie Ma, MD, PhD   +7 more
doaj   +1 more source

Retina and glaucoma: surgical complications

International Journal of Retina and Vitreous, 2018
Background The close structural and microcirculatory co-relation between anterior and posterior segments of eye make them very vulnerable to complications when one of them is affected surgically.
Niroj Kumar Sahoo, Pasyanthi Balijepalli, Sumit Randhir Singh, Mahima Jhingan, Sirisha Senthil, Jay Chhablani   +5 more
doaj   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

The critical role of m6A methylation in the pathogenesis of Graves' ophthalmopathy

Eye and Vision, 2020
Purpose To investigate the role of N6-methyladenosine (m6A) RNA modification in the pathogenesis of Graves' ophthalmopathy (GO). Methods Surgically excised extraocular muscles from 7 patients with GO and 5 subjects without GO were used.
Li Zhu, Siyan Li, Shikun He, Qizhe Tong, Lejin Wang, Xiaohua Li, Xi Wu, Qingyu Meng, Enzhong Jin, Chuan Zhang, Tianyuan Li, Ningda Xu, Lvzhen Huang, Yi Wang, Mingwei Zhao   +14 more
doaj   +1 more source

Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila

Advanced Science, EarlyView.
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu, Xuedi Zhang, Ying Zhou, Jie Zheng, Angyang Sun, Kailong Zhuang, Weiwei Bao, Guanjun Gao   +7 more
wiley   +1 more source

Unmasking of molecular players: proteomic profiling of vitreous humor in pathologic myopia

BMC Ophthalmology
Background This study aimed to identify the differentially expressed proteins in the vitreous humor (VH) of eyes with and without pathologic myopia (PM), providing insights into the molecular pathogenesis.
Yue Wen, Chi Ren, Li Zhu, Lvzhen Huang, Huijun Qi, Wenzhen Yu, Kai Wang, Mingwei Zhao, Qiong Xu   +8 more
doaj   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Correction: PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function

Cell Communication and Signaling, 2023
Lijie Dong, Wenbo Li, Tingting Lin, Boshi Liu, Yaru Hong, Xiaomin Zhang, Xiaorong Li   +6 more
doaj   +1 more source

Enhancing retinal images by nonlinear registration

, 2014
Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a few.
Chenegros, Guillaume, Glanc, Marie, Molodij, Guillaume, Ribak, Erez N.   +3 more
core   +3 more sources