Results 151 to 160 of about 205,905 (259)

The Clinical Significance of Imaging Biomarkers Discoverable by Anomaly Detection Methods in Retinal Diseases: A Review. [PDF]

J Ophthalmol
Wittmann AM, Seeböck P, Heger KA, Egger D, Langs G, Waldstein SM.   +5 more
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Expanding horizons of intravitreal anti-vascular endothelial growth factor therapy in retinal diseases. [PDF]

Indian J Ophthalmol
Singh S, Kala U, Bamel A, Agarwal M.
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Development and standardisation of 'time-in-range' measurement for clinical endpoints in retinal diseases. [PDF]

Eye (Lond)
Frizziero L, Barratt J, Cheung CMG, Korol A, Midena E, Talks J, Tsilimbaris M, Pearce I, Kozak I.   +8 more
europepmc   +1 more source

From Genetic Diagnosis to Therapeutic Implementation in Retinal Diseases: Translational Advances and Persistent Bottlenecks. [PDF]

Biomedicines
Menna F, Pinelli C, De Luca L, Meduri A, Baldascino A, Lupo S, Vingolo EM.   +6 more
europepmc   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Assessment of In-Frame Indel Variants in an Unsolved Cohort of Inherited Retinal Diseases Using Machine Learning. [PDF]

Hum Mutat
Rauch DE, Wang M, Hafiz MJH, Brock DC, Li Y, Marra M, Pennesi ME, Yang P, Lesley E, Lopez I, Koenekoop R, Collantes ER, Bolinao J, Chen R.   +13 more
europepmc   +1 more source

Low‐Dose Atropine for Myopia Control in Children: A Comprehensive Review With Indian Evidence

Eye &ENT Research, EarlyView.
ABSTRACT Myopia is an increasingly prevalent public health concern in India, particularly among school‐aged children in urban and academically demanding environments. Early‐onset myopia is associated with rapid progression and an increased lifetime risk of vision‐threatening complications such as retinal detachment, myopic maculopathy, glaucoma, and ...
Ragni Kumari
wiley   +1 more source