Results 151 to 160 of about 2,469,822 (264)

Editorial: Global perspectives on genetic diagnosis and treatments for inherited retinal diseases. [PDF]

Front Ophthalmol (Lausanne)
Murakami Y, Liu PK, Windy DA, Shrestha A.   +3 more
europepmc   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Retinal Diseases: Mechanisms, Diagnosis and Treatments-From Mechanistic Insights to Personalized Retina Care. [PDF]

J Pers Med
Stanca HT.
europepmc   +1 more source

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

Animal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund, Brian LaMendola, Nathan P. Crilly, Seth Kittle, Betsy M. Ferguson, Anne D. Lewis, Jeff Wall, Samuel M. Peterson   +7 more
wiley   +1 more source

An Update on Retinal Diseases: From Diagnosis to Treatment. [PDF]

J Clin Med
Honda S, Sugimoto M, Yamashiro K.
europepmc   +1 more source

Artificial intelligence in assessing cardiovascular diseases and risk factors via retinal fundus images: A review of the last decade

Cardiovascular diseases (CVDs) are the leading cause of death globally. The use of artificial intelligence (AI) methods—in particular, deep learning (DL)—has been on the rise lately for the analysis of different CVD-related topics.
Pourmoghtader, Keysan, Ghafouri-Asbagh, Amirhosein, Jafarizadeh, Ali, Alizadehsani, Roohallah, Acharya, U. Rajendra, Sobhi, Navid, Asadi, Houshyar, Tan, Ru-San, Abdollahi, Mirsaeed, Pedrammehr, Siamak   +9 more
core   +1 more source

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, EarlyView.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source

Ciliary Defects in Inherited Retinal Diseases. [PDF]

Adv Genet (Hoboken)
Guo G, Li L, Zhou J, Ran J.
europepmc   +1 more source

CD44, ACAN, PLVAP, and HBEGF Emerged as Potential Biomarkers in Diabetic Retinopathy

Diabetes, Metabolic Syndrome and Obesity
Qingbo Li,1,* Xu Zhou,1,* Ying Wang,2,* Yi Peng,1 Juping Liu,1 Xiaorong Li,1 Yan Shao1,2 1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye ...
Li Q, Zhou X, Wang Y, Peng Y, Liu J, Li X, Shao Y   +6 more
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