Results 281 to 290 of about 9,860,660 (392)

Diagnosing Retinal Eye Diseases: A Novel Transfer Learning Approach [PDF]

Mohammed Salih Ahmed, Yahya Alhabboub, Khalid J. Alzahrani, Hassan Baragbah, Basel Altaha, Hussein Alkatout, Aghiad Bakry, Atta Rahman, Sardar Asad Ali Biabani, Rashad Ahmed   +9 more
openalex   +1 more source

Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1237-1245, April 2025.
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri, Ahmad Gharaibeh, Lubika Nkashama, Abdelrahman Abushouk, Osama Abushawer, Amir Mehdizadeh‐Shrifi, Bianca Honnekeri, Cassandra Calabrese, Venu Menon, Pauline Funchain, Patrick Collier, Diego Sadler, Rohit Moudgil   +12 more
wiley   +1 more source

Base and Prime Editing for Inherited Retinal Diseases: Delivery Platforms, Safety, Efficacy, and Translational Perspectives. [PDF]

Pharmaceutics
Zhang H, Li Y, Li J, Li X, Li T.
europepmc   +1 more source

Memantine treatment in individuals with GRIN gain‐of‐function variants is associated with improvements in behavior, development, and seizure frequency

Epilepsia, EarlyView.
Abstract Objective GRIN‐related disorders due to pathogenic variants in GRIN1, GRIN2A, GRIN2B, or GRIN2D genes are associated with altered N‐methyl‐D‐aspartate receptor (NMDAR) function. Functional changes include gain (GoF) and loss of receptor function (LoF). Clinical reports describing the use of the NMDAR blocker memantine in GRIN‐related disorders
Maike Karnstedt, Riley E. Perszyk, Scott J. Myers, Ellington McDaniels, Marta Somorai, Ingo Borggraefe, Danielle C. M. Veenma, An‐Sofie Schoonjans, Pasquale Striano, Tadeu A. Fantaneanu, Steffen Syrbe, Kristen Park, Wenjuan Chen, Hongjie Yuan, Stephen F. Traynelis, Timothy A. Benke, Johannes R. Lemke, Ilona Krey   +17 more
wiley   +1 more source

Cystoid Macular Lesions in Inherited Retinal Diseases: Prevalence, Characteristics, and Genetic Associations in a Hungarian Cohort. [PDF]

Genes (Basel)
Asboth B, Sanrocco A, Besztercei B, Lesch B, Takacs A, Vamos R, Varsanyi B, Vegh A, Knezy K, Szabo V, Nagy ZZ, Zobor D.   +11 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Pericytes as Key Players in Retinal Diseases: A Comprehensive Narrative Review. [PDF]

Biology (Basel)
D'Esposito F, Cappellani F, Visalli F, Capobianco M, Rapisarda L, Avitabile A, Cannizzaro L, Malaguarnera R, Gagliano G, Maniaci A, Lentini M, Montalbano G, Zaouali MA, H'mida D, Giurdanella G, Gagliano C.   +15 more
europepmc   +1 more source

Normal Human Corneal Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cells as a Model to Study Human Retinal Diseases

, 2019
Roy Joseph, O. P. Srivastava, Roswell R. Pfister   +2 more
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

HyReti-Net: hybrid retinal diseases classification and diagnosis network using optical coherence tomography. [PDF]

Front Med (Lausanne)
Yang J, Hsu C, Wang J, Wu B, Lu Y, Ding Y, Zhao Z, Tang K, Lu F, Ma L.   +9 more
europepmc   +1 more source