Results 111 to 120 of about 321,318 (176)

Transmission Electron Microscopy Data on drusen-like deposits in the retinal degeneration sTg-IRBP: HEL mouse model

Data in Brief, 2019
Histology (H&E) and transmission electron microscopy (TEM) data are provided showing age-related changes in the retinal structure of sTg-IRBP:HEL mice.
Yi-Hsia Liu, Christine Mölzer, Gillian C. Milne, Lucia Kuffová, John V. Forrester   +4 more
doaj  

PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in the retinal pigment epithelium

Cell Death and Disease
Drusen, the yellow deposits under the retina, are composed of lipids and proteins, and represent a hallmark of age-related macular degeneration (AMD). Lipid droplets are also reported in the retinal pigment epithelium (RPE) from AMD donor eyes.
Shuyan Zhou, Kaan Taskintuna, Jacob Hum, Jasmine Gulati, Stephanie Olaya, Jeremy Steinman, N. Golestaneh   +6 more
semanticscholar   +1 more source

Macular dysfunction in drusen maculopathy assessed with multifocal electroretinogram and optical coherence tomography

Clinical Ophthalmology, 2013
Jose G Garcia-Garcia,1,2 Jose M Ruiz-Moreno,1 Kristina Holm,2 Sten Andréasson,2 Monica Lövestam-Adrian21Department of Ophthalmology, University of Castilla La Mancha, Albacete, Spain; 2Department of Ophthalmology, University of Lund, Lund ...
Garcia-Garcia JG, Ruiz-Moreno JM, Holm K, Andreasson S, Lövestam-Adrian M   +4 more
doaj  

Simplified Convolutional Neural Network Model for Automatic Classification of Retinal Diseases from Optical Coherence Tomography Images

مجلة النهرين للعلوم الهندسية
Optical coherence tomography (OCT) allows for direct and immediate imaging of the morphology of retinal tissue. It has become a crucial imaging modality for diagnosing eye problems in ophthalmology.
Noor B. Khalaf, Hadeel K. Aljobouri, Mohammed S. Najim, Ilyas Çankaya   +3 more
doaj   +1 more source

This actually looks like that: Proto-BagNets for local and global interpretability-by-design [PDF]

arXiv
Interpretability is a key requirement for the use of machine learning models in high-stakes applications, including medical diagnosis. Explaining black-box models mostly relies on post-hoc methods that do not faithfully reflect the model's behavior. As a remedy, prototype-based networks have been proposed, but their interpretability is limited as they ...
arxiv  

OCT Data is All You Need: How Vision Transformers with and without Pre-training Benefit Imaging [PDF]

arXiv
Optical Coherence Tomography (OCT) provides high-resolution cross-sectional images useful for diagnosing various diseases, but their distinct characteristics from natural images raise questions about whether large-scale pre-training on datasets like ImageNet is always beneficial.
arxiv  

Longitudinal analysis of retinal thickness and retinal function in eyes with large drusen secondary to intermediate age-related macular degeneration.

Ophthalmology Retina, 2020
M. Saßmannshausen, Jing Zhou, M. Pfau, S. Thiele, J. Steinberg, M. Fleckenstein, F. Holz, S. Schmitz-Valckenberg   +7 more
semanticscholar   +1 more source

Adaptive Multiscale Retinal Diagnosis: A Hybrid Trio-Model Approach for Comprehensive Fundus Multi-Disease Detection Leveraging Transfer Learning and Siamese Networks [PDF]

arXiv
WHO has declared that more than 2.2 billion people worldwide are suffering from visual disorders, such as media haze, glaucoma, and drusen. At least 1 billion of these cases could have been either prevented or successfully treated, yet they remain unaddressed due to poverty, a lack of specialists, inaccurate ocular fundus diagnoses by ophthalmologists,
arxiv  

Reticular Pseudodrusen

Ophthalmology Science
Purpose: To understand the spatial relationship between local rod-mediated visual function and reticular pseudodrusen (RPD) in eyes with large drusen. Design: Retrospective cross-sectional study.
Himeesh Kumar, MBBS(Hons), PhD, Robyn H. Guymer, MBBS, PhD, Lauren A.B. Hodgson, MPH, Xavier Hadoux, MEng, PhD, Maxime Jannaud, MEng, Peter van Wijngaarden, MBBS(Hons), PhD, Chi D. Luu, PhD, Zhichao Wu, BAppSc(Optom), PhD   +7 more
doaj  

In vitro drusen model – three-dimensional spheroid culture of retinal pigment epithelial cells

Journal of Cell Science, 2019
Hideaki Usui, Akiko Nishiwaki, Lanors Landiev, J. Kacza, W. Eichler, Rina Wako, A. Kato, N. Takase, S. Kuwayama, K. Ohashi, Y. Yafai, A. Bringmann, Ayae Kubota, Y. Ogura, J. Seeger, P. Wiedemann, T. Yasukawa   +16 more
semanticscholar   +1 more source