Results 111 to 120 of about 29,682 (236)

INTRAVITREAL INJECTION OF AUTOLOGOUS BONE MARROW-DERIVED MONONUCLEAR CELLS FOR HEREDITARY RETINAL DYSTROPHY A Phase I Trial

open access: yes, 2011
Purpose: To evaluate the short-term (10 months) safety of a single intravitreal injection of autologous bone marrow-derived mononuclear cells in patients with retinitis pigmentosa or cone-rod dystrophy.
Rubens C Siqueira   +9 more
core   +1 more source

Gene Panel Analysis Reveals Overlapping Genetic Causes of Inherited Cataracts and Other Ocular Phenotypes in Bulgarian Patients

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
We have identified 4 pathogenic/likely pathogenic changes and 2 variants of uncertain significance, 3 of which were novel. The identification of disease‐causing variants in the CRYAA, MYH9, RP2, and CLNC1 genes allowed us to establish an accurate genetic diagnosis of inherited cataract and to describe overlapping clinical phenotypes.
Kristiyana Vitanova   +10 more
wiley   +1 more source

Low‐Cost and Detunable Wireless Resonator Glasses for Enhanced Eye MRI With Concurrent High‐Quality Whole‐Brain MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 1, Page 499-507, July 2026.
ABSTRACT Purpose To develop a wearable wireless resonator glasses design that enhances eye MRI signal‐to‐noise ratio (SNR) without compromising whole‐brain image quality at 7 T. Methods The device integrates two detunable LC loop resonators into a lightweight, 3D‐printed frame positioned near the eyes.
Ming Lu   +7 more
wiley   +1 more source

A comparative study of the potential for human retinal pigment epithelium utilising an embryonic chick model of the phenomenon

open access: yes, 2014
The retinal pigment epithelial (RPE) cells of several species, including: chicken, rat, mouse and newt, have been observed to undergo a phenomenon known as transdifferentiation.
Smart, MJK
core  

Repeatability of SpotChecks contrast sensitivity test in macular disease

open access: yesOptometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose SpotChecks is an accessible contrast sensitivity test with good repeatability in healthy adults. This study compared its intra‐visit repeatability with the near Pelli–Robson test in adults with macular disease. Methods One eye from 29 adults with macular disease (mean age 71 ± 13 years) underwent high‐contrast logMAR acuity and two ...
Katlyn B. Sprague   +4 more
wiley   +1 more source

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina.

open access: yes, 2014
Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their ...
Ortín-Martínez, A   +8 more
core  

Adult-onset Foveomacular Vitelliform Dystrophy

open access: yes
Adult-onset foveomacular vitelliform dystrophy is one of the most common macular dystrophies, classified within the group of pattern dystrophies. The condition typically arises after the fourth decade of life and manifests with subretinal vitelliform ...
Michał Jabłoński, Jerzy Mackiewicz
core   +1 more source

Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy.

open access: yes, 2011
PURPOSE. To characterize anatomically and functionally the retinal degeneration observed in a transgenic mouse line (OPN1LW-EGFP) expressing enhanced green fluorescent protein (EGFP) in a subpopulation of cone photoreceptors, and to map the location of ...
Charbel Issa, P   +34 more
core   +1 more source

Reflections on emerging therapies for inherited retinal diseases following a community education event: A qualitative exploration

open access: yesOptometry and Vision Science, Volume 103, Issue 7, July 2026.
ABSTRACT Purpose To explore the inherited retinal diseases (IRD) communities' attitudes and perspective toward emerging therapies—specifically gene therapy, cell therapy, and retinal prostheses—following a community education event. Methods At an in‐person half‐day IRD community education event, subject‐matter experts presented the scientific ...
Eden G. Robertson   +4 more
wiley   +1 more source

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