Results 51 to 60 of about 188,294 (288)

Analysis of normal human retinal vascular network architecture using multifractal geometry

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To apply the multifractal analysis method as a quantitative approach to a comprehensive description of the microvascular network architecture of the normal human retina.
Ştefan Ţălu   +4 more
doaj   +1 more source

Diurnal variation of optical coherence tomography–based macular fluid in exudative age-related macular degeneration

open access: yesInternational Journal of Retina and Vitreous, 2023
Background Significant diurnal fluctuation of optical coherence tomography (OCT)-based macular fluid occurs in patients with several macular conditions including diabetic macular edema (DME) and cystoid macular edema due to retinal venous occlusion (RVO).
Blake H. Fortes   +5 more
doaj   +1 more source

Repeatability of \u3cem\u3eIn Vivo\u3c/em\u3e Parafoveal Cone Density and Spacing Measurements [PDF]

open access: yes, 2012
Purpose. To assess the repeatability and measurement error associated with cone density and nearest neighbor distance (NND) estimates in images of the parafoveal cone mosaic obtained with an adaptive optics scanning light ophthalmoscope (AOSLO).Methods ...
Carroll, Joseph   +5 more
core   +1 more source

Enhancing retinal images by nonlinear registration

open access: yes, 2014
Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a few.
Chenegros, Guillaume   +3 more
core   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Enhancement and labelling of OCT images

open access: yesCurrent Directions in Biomedical Engineering, 2023
Optical Coherence Tomography (OCT) is a noninvasive technique for visualizing retinal cross-sections, assisting in diagnosing and monitoring retinal diseases. This study presents an effective OCT image noise reduction and segmentation method.
Karthik Karri, Mahadevappa Manjunatha
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

A smartphone-based tool for rapid, portable, and automated wide-field retinal imaging [PDF]

open access: yes, 2018
Purpose:High-quality, wide-field retinal imaging is a valuable method for screening preventable, vision-threatening diseases of the retina. Smartphone-based retinal cameras hold promise for increasing access to retinal imaging, but variable image quality
Margolis, Todd
core   +4 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Colour normalisation to reduce inter-patient and intra-patient variability in microaneurysm detection in colour retinal images [PDF]

open access: yes, 2005
Images of the human retina vary considerably in their appearance depending on the skin pigmentation (amount of melanin) of the subject. Some form of normalisation of colour in retinal images is required for automated analysis of images if good ...
Cornforth, D.J.   +2 more
core  

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