Results 111 to 120 of about 238,742 (294)
Purpose: To identify factors associated with accelerated retinal aging based on machine learning predictions of age using fundus images from teleretinal screening of patients with diabetes. Design: Cross-sectional study of retinal images.
Tuyet Thao Nguyen, BS +8 more
doaj +1 more source
Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu +7 more
wiley +1 more source
Many ophthalmic and systemic diseases can be screened by analyzing retinal fundus images. The clarity and resolution of retinal fundus images directly determine the effectiveness of clinical diagnosis.
Yanfei Jia, Guangda Chen, Haotian Chi
doaj +1 more source
\u3cem\u3eIn vivo\u3c/em\u3e Dark-field Imaging of the Retinal Pigment Epithelium Cell Mosaic [PDF]
Non-invasive reflectance imaging of the human RPE cell mosaic is demonstrated using a modified confocal adaptive optics scanning light ophthalmoscope (AOSLO). The confocal circular aperture in front of the imaging detector was replaced with a combination
Dubra, Alfredo +2 more
core +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
Solid Harmonic Wavelet Bispectrum for Image Analysis
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown +3 more
wiley +1 more source
The cellular-level visualization of retinal microstructures such as blood vessel wall components, not available with other imaging modalities, is provided with unprecedented details by dark-field imaging configurations; however, the interpretation of ...
Mircea Mujat +8 more
doaj +1 more source
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
Learnable Diffusion Framework for Mouse V1 Neural Decoding
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng +2 more
wiley +1 more source

