Results 31 to 40 of about 614,157 (313)

Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers

open access: yesPLoS ONE, 2022
Purpose Peripheral T cell CXCR3 expression has been found uniquely lower in patients having neovascular age-related macular degeneration (nAMD) than in healthy individuals. The CXCR3-axis has been shown to have angiostatic and antifibrotic properties. We
Charlotte Liisborg   +4 more
doaj   +2 more sources

Pars plana vitrectomy and laser photocoagulation of vasoproliferative tumors: a new surgical approach to sight-threatening complications [PDF]

open access: yesRevista Brasileira de Oftalmologia
Retinal vasoproliferative tumor is a rare disease associated with several sight-threatening complications. The optimum management of retinal vasoproliferative tumor is unknown and the need of surgery arises when there is diagnostic uncertainty or sight ...
Aline Fernandes de Albuquerque   +3 more
doaj   +1 more source

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

open access: yes, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev   +6 more
core   +1 more source

Ocular manifestations in Gorlin-Goltz syndrome [PDF]

open access: yes, 2019
Background: Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is a rare genetic disorder that is transmitted in an autosomal dominant manner with complete penetrance and variable expressivity.
Franzone, F.   +8 more
core   +1 more source

Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment [PDF]

open access: yes, 2018
Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal ...
Apte, Rajendra   +3 more
core   +3 more sources

Retinoblastoma and Retinal Astrocytoma: Unusual Double Tumor in One Eye [PDF]

open access: yesActa Medica Iranica, 2011
Retinoblastoma is the most common intraocular neoplasm in children. Glial tumor of the retina and optic nerve head are considered to be congenital and are therefore classified as hamartomas.
Fahimeh Asadi Amoli   +2 more
doaj   +2 more sources

RPE Adenocarcinoma as the Presenting Sign of Bronchogenic Carcinoma: Diagnostic Dilemma in the Management of a Case

open access: yesCase Reports in Ophthalmological Medicine, 2013
Neoplasms of retinal pigment epithelium are rare and must be differentiated from choroidal melanoma. The possibility of a metastatic disease with possible primary sites as lung, breast, or kidney should be ruled out.
Namrata Adulkar   +3 more
doaj   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

open access: yes, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

Busulfan Treatment for Myeloproliferative Disease may Reduce Injection Burden in Vascular Endothelial Growth Factor-Driven Retinopathy

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: Myeloproliferative neoplasms (MPNs) have been associated with increased systemic levels of vascular endothelial growth factor (VEGF). This study investigated an association between systemic busulfan for treatment of MPN and the requirement for ...
Lauren A. Dalvin   +5 more
doaj  

Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]

open access: yes, 2018
We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo   +41 more
core   +5 more sources

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