Results 31 to 40 of about 654,251 (322)

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

A partial gene deletion of SLC45A2 causes oculocutaneous albinism in Doberman pinscher dogs. [PDF]

PLoS ONE, 2014
The first white Doberman pinscher (WDP) dog was registered by the American Kennel Club in 1976. The novelty of the white coat color resulted in extensive line breeding of this dog and her offspring.
Paige A Winkler, Kara R Gornik, David T Ramsey, Richard R Dubielzig, Patrick J Venta, Simon M Petersen-Jones, Joshua T Bartoe   +6 more
doaj   +1 more source

Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment [PDF]

, 2018
Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal ...
Apte, Rajendra, Lin, Jonathan, Sein, Julia, Van Stavern, Gregory   +3 more
core   +3 more sources

Red Blood Cells: Tethering, Vesiculation, and Disease in Micro-Vascular Flow

Diagnostics, 2021
The red blood cell has become implicated in the progression of a range of diseases; mechanisms by which red cells are involved appear to include the transport of inflammatory species via red cell-derived vesicles.
Robert J. Asaro, Pedro Cabrales
doaj   +1 more source

Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]

, 2018
We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo, Barbui, Tiziano, Beggiato, Eloise, Bellini, Marta, Bertozzi, Irene, Betti, Silvia, Bonifacio, Massimiliano, Cacciola, Emma, Cacciola, Rossella, Carli, Giuseppe, Carobbio, Alessandra, Cattaneo, Daniele, Cazzola, Mario, Censori, Bruno, Cervantes, Francisco, Cortelezzi, Agostino, De Stefano, Valerio, Di Lazzaro, Vincenzo, Elli, Elena Maria, Ellis, Martin H., Finazzi, Guido, Finazzi, Maria Chiara, Gaidano, Gianluca, Gomez, Montse, Griesshammer, Martin, Guglielmelli, Paola, Hernandez-Boluda, Juan-Carlos, Iurlo, Alessandra, Loscocco, Giuseppe Gaetano, Lunghi, Francesca, Miroslava, Palova, Musolino, Caterina, Palandri, Francesca, Randi, Maria Luigia, Rapezzi, Davide, Rossi, Elena, Rumi, Elisa, Sadjadian, Parvis, Scaffidi, Luigi, Tieghi, Alessia, Vannucchi, Alessandro M., Vianelli, Nicola   +41 more
core   +5 more sources

Patients with myeloproliferative neoplasms and high levels of systemic inflammation develop age-related macular degeneration

EClinicalMedicine, 2020
Background: Epidemiological data show that myeloproliferative neoplasms (MPNs) are associated with increased risk of neovascular age-related macular degeneration (AMD). However, knowledge about the retinal findings in these patients is lacking.
Charlotte Liisborg, Marie Krogh Nielsen, Hans Carl Hasselbalch, Torben Lykke Sørensen   +3 more
doaj   +1 more source

Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers.

PLoS ONE, 2022
PurposePeripheral T cell CXCR3 expression has been found uniquely lower in patients having neovascular age-related macular degeneration (nAMD) than in healthy individuals. The CXCR3-axis has been shown to have angiostatic and antifibrotic properties.
Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen   +4 more
doaj   +2 more sources

Pars plana vitrectomy and laser photocoagulation of vasoproliferative tumors: a new surgical approach to sight-threatening complications [PDF]

Revista Brasileira de Oftalmologia
Retinal vasoproliferative tumor is a rare disease associated with several sight-threatening complications. The optimum management of retinal vasoproliferative tumor is unknown and the need of surgery arises when there is diagnostic uncertainty or sight ...
Aline Fernandes de Albuquerque, Patricia A Correa, Moyses Zajdenweber, Oswaldo F Moura Brasil   +3 more
doaj   +1 more source

Imaging of adult ocular and orbital pathology - a pictorial review [PDF]

, 2014
Orbital pathology often presents a diagnostic challenge to the reporting radiologist. The aetiology is protean, and clinical input is therefore often necessary to narrow the differential diagnosis.
Brennan, Paul, Galvin, Patrick Leo, Grech, Reuben, Grech, Stephan, Looby, Seamus, Mizzi, Adrian, O'Hare, Alan, Spiteri Cornish, Kurt, Thornton, John   +8 more
core   +1 more source

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]

, 2016
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM, Brown-Frandsen, K, Buse, JB, Daniels, GH, Kristensen, P, LEADER Steering Committee on behalf of the LEADER Trial Investigators, Mann, JF, Marso, SP, Nauck, MA, Nissen, SE, Pocock, S, Poulter, NR, Ravn, LS, Steinberg, WM, Stockner, M, Zinman, B   +15 more
core   +1 more source