Results 151 to 160 of about 24,689 (278)

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Peripapillary Retinal Nerve Fiber Layer Thickness in Diabetic Retinopathy Patients measured by Optical Coherence Tomography

IJRETINA (International Journal of Retina), 2018
Introduction: Diabetic retinopathy (DR) is a microvascular complication of diabetes and one of the leading causes of blindness. Retinal function loss in diabetic patients is not only caused by microvascular abnormality but also retinal neurodegeneration.
Sindi Dwijayanti, Arief Kartasasmita, Iwan Sovani, Erwin Iskandar, Rova Virgana, Grimaldi Ihsan   +5 more
doaj  

Beyond intracranial pressure: Cerebrospinal fluid compartmentalization in spaceflight‐associated neuro‐ocular syndrome

Experimental Physiology, EarlyView.
Susan P. Mollan, Damian M. Bailey
wiley   +1 more source

Hyperreflective Foci in the Inner Nuclear Layer: Proof‐of‐Concept for an Optical Coherence Tomography Derived Microglia‐Related Marker in Multiple Sclerosis

Annals of Neurology, Volume 99, Issue 6, Page 1480-1485, June 2026.
The role of microglia has emerged as a critical driver of disease progression in multiple sclerosis (MS), but we lack broadly applicable monitoring tools. Here, we investigated whether hyperreflective foci (HRF), as detected by optical coherence tomography (OCT) within the inner nuclear layer (INL) of the retina, can be used as a marker for microglial ...
Jonathan A. Gernert, Laura M. Bartos, Tara Christmann, Hanna Zausinger, Luca N. Diedrich, Daniel Engels, Miriam Schlüter, Sarah Schlaeger, Sophia Stoecklein, Leonie F. Keidel, Tania Kümpfel, Martin Kerschensteiner, Matthias Brendel, Joachim Havla   +13 more
wiley   +1 more source

Pseudotumor Cerebri Syndrome and Essential Thrombocythemia: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pseudotumor cerebri syndrome (PTCS) is characterized by elevated intracranial pressure in the absence of intracranial mass lesions, structural abnormalities, or infectious conditions. Although the exact pathogenesis of PTCS remains largely elusive, it is increasingly recognized as a multifactorial condition.
Fang‐Tzu Chang, Yi‐Ying Chen, Fu‐Yu Lin   +2 more
wiley   +1 more source

MOG Antibody‐Associated Optic Neuritis Masquerading as Traumatic Optic Neuropathy Following Cranial Trauma: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is an autoimmune disorder characterized by demyelination of the central nervous system. It can impact the optic nerves, spinal cord, brain parenchyma, and brainstem, resulting in various clinical presentations such as acute disseminated encephalomyelitis (ADEM), optic ...
Yuxian Shi, Xin Qi, Boding Tong, Jing Deng, Yating Liu, Yunping Li   +5 more
wiley   +1 more source

Electric Cataract After High‐Voltage Craniofacial Injury With Preserved Optic Nerve Microvasculature: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT High‐voltage craniofacial electrical injury may result in delayed cataract without optic nerve damage. Multimodal structural and functional assessment supports accurate prognostication, and when posterior segment integrity is preserved, visual recovery after cataract surgery is typically excellent and sustained.
Md Iftekher Iqbal, Fariah Osman
wiley   +1 more source

Retinal nerve fiber layer thickness in epilepsy: a meta-analysis comparing affected patients with healthy controls. [PDF]

BMC Ophthalmol
Jiangyi L, Shuping L, Yulei S, Congdon N, Lei C, Yuanbo L.   +5 more
europepmc   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

Advanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source