Results 131 to 140 of about 24,689 (278)

Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell‐ and nano‐scale process extension for neural repair applications

Journal of Anatomy, Volume 246, Issue 4, Page 585-601, April 2025.
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
Cian O'Connor, Rena E. Mullally, Sarah F. McComish, Julia O'Sullivan, Ian Woods, Ingmar Schoen, Massimiliano Garre, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +9 more
wiley   +1 more source

Changes in retinal nerve fiber layer and optic disc algorithms by optical coherence tomography in glaucomatous Arab subjects

, 2013
Ferial M Zeried, Uchechukwu L Osuagwu Department of Optometry and Vision Sciences College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia Purpose: To assess the difference in retinal nerve fiber layer (RNFL) and optic ...
Zeried FM, Osuagwu UL
core  

Variability of HRT3 mean retinal nerve fiber layer thickness by retinal regions among HIV+ and HIV-seronegative patients.

, 2015
HRT = Heidelberg retina tomography, HIV+ = subjects who are human immunodeficiency virus (HIV) positive, HIV- = subjects who are HIV negative controls, CD4 = CD4 cell count, SD = standard deviation, RNFL = retinal nerve fiber layer, Sup = superior, Inf =
Igor Grant (132637), Igor Kozak (459746), Robert N. Weinreb (170002), William R. Freeman (459747), Byung Ro Lee (781840), Victoria L. Knudsen (781839), Dirk-Uwe Bartsch (459753)   +6 more
core   +1 more source

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, EarlyView.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

Comparison of global and sectorial retinal nerve fiber layer thickness (RNFLT) measurements by race.

, 2018
Comparison of global and sectorial retinal nerve fiber layer thickness (RNFLT) measurements by race.
Alexandre S. C. Reis (6095894), Jamil Miguel-Neto (6095897), Jayme R. Vianna (6095891), Vital P. Costa (740069), Balwantray C. Chauhan (317925), Claude F. Burgoyne (476921), Camila S. Zangalli (6095888)   +6 more
core   +1 more source

Selumetinib as a Target Therapy in Progressive Paediatric Low‐Grade Gliomas—Case Series (pLGG)

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Optic pathway gliomas (OPGs) occur in 15%–20% of children with neurofibromatosis type 1 (NF1). While smaller gliomas may be only monitored, the current standard of care for symptomatic ones relies on chemotherapy, most commonly carboplatin and vincristine.
Laura Trapani, Giulia Gortani, Andrea Magnolato, Flora Maria Murru, Elisabetta Cattaruzzi, Laura Diplotti, Paola Michieletto, Silvia Giganti, Davide Zanon, Alessandra Maestro, Valentina Kiren, Egidio Barbi, Irene Bruno   +12 more
wiley   +1 more source

Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography

Acta Neuropathologica Communications
Excitotoxicity from the impairment of glutamate uptake constitutes an important mechanism in neurodegenerative diseases such as Alzheimer’s, multiple sclerosis, and Parkinson's disease. Within the eye, excitotoxicity is thought to play a critical role in
Da Ma, Wenyu Deng, Zain Khera, Thajunnisa A. Sajitha, Xinlei Wang, Gadi Wollstein, Joel S. Schuman, Sieun Lee, Haolun Shi, Myeong Jin Ju, Joanne Matsubara, Mirza Faisal Beg, Marinko Sarunic, Rebecca M. Sappington, Kevin C. Chan   +14 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Evaluation of retinal nerve fiber layer thickness measurement following laser in situ keratomileusis using scanning laser polarimetry

Indian Journal of Ophthalmology, 2007
Aim: To evaluate the effect of laser-assisted in situ keratomileusis (LASIK) on the measurement of retinal nerve fiber layer thickness by scanning laser polarimetry using customized corneal compensation in myopes.
Dada Tanuj, Chaudhary Sunil, Muralidhar Rajamani, Nair Soman, Sihota Ramanjit, Vajpayee Rasik   +5 more
doaj