Results 1 to 10 of about 109,464 (277)
Neural Regeneration Research, 2023 [INLINE:1] Vision depends on accurate signal conduction from the retina to the brain through the optic nerve, an important part of the central nervous system that consists of bundles of axons originating from retinal ganglion cells.
Zhe Liu +12 more
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Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma. [PDF]
PLoS ONE, 2013 Glaucoma is a complex disease affecting an estimated 70 million people worldwide, characterised by the progressive degeneration of retinal ganglion cells and accompanying visual field loss.
Pete A Williams +6 more
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PTEN Expression Regulates Gap Junction Connectivity in the Retina
Frontiers in Neuroanatomy, 2021 Manipulation of the phosphatase and tensin homolog (PTEN) pathway has been suggested as a therapeutic approach to treat or prevent vision loss due to retinal disease.
Ashley M. Chen +7 more
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Inhibition of BDNF-AS Provides Neuroprotection for Retinal Ganglion Cells against Ischemic Injury. [PDF]
PLoS ONE, 2016 Brain-derived neurotrophic factor (BDNF) protects retinal ganglion cells against ischemia in ocular degenerative diseases. We aimed to determine the effect of BDNF-AS on the ischemic injury of retinal ganglion cells.The levels of BDNF and BDNF-AS were ...
Lifang Xu +4 more
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Neural Regeneration Research, 2023 Ras homolog enriched in brain (Rheb) is a small GTPase that activates mammalian target of rapamycin complex 1 (mTORC1). Previous studies have shown that constitutively active Rheb can enhance the regeneration of sensory axons after spinal cord injury by ...
Jikuan Jiang +7 more
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Distinct roles for inhibition in spatial and temporal tuning of local edge detectors in the rabbit retina. [PDF]
, 2014 This paper examines the role of inhibition in generating the receptive-field properties of local edge detector (LED) ganglion cells in the rabbit retina. We confirm that the feed-forward inhibition is largely glycinergic but, contrary to a recent report,
Buldyrev, Ilya +5 more
core +7 more sources
In vivo chromatic and spatial tuning of foveolar retinal ganglion cells in Macaca fascicularis.
PLoS ONE, 2022 The primate fovea is specialized for high acuity chromatic vision, with the highest density of cone photoreceptors and a disproportionately large representation in visual cortex.
Tyler Godat +10 more
doaj +2 more sources
Uptake of Retrograde Tracers by Intact Optic Nerve Axons: A New Way to Label Retinal Ganglion Cells. [PDF]
PLoS ONE, 2015 Retrograde labelling of retinal ganglion cells with optic nerve transection often leads to degeneration of ganglion cells in prolonged experiments. Here we report that an intact optic nerve could uptake retrograde tracers applied onto the surface of the ...
Yu-Xiang Liang +3 more
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Frontiers in Cell and Developmental Biology, 2022 Radiation retinopathy (RR) is a common complication following radiation therapy of globe, head, and neck malignancies, and is characterized by microangiopathy, neuroretinopathy, and the irreversible loss of visual function. To date, there is no effective
Siyu Chen +21 more
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Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation. [PDF]
, 1991 The integrin alpha 6 beta 1 is a prominent laminin receptor used by many cell types. In the present work, we isolate clones and determine the primary sequence of the chick integrin alpha 6 subunit.
de Curtis, I +3 more
core +3 more sources