Results 51 to 60 of about 689,309 (95)
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu +7 more
wiley +1 more source
Syntaxin‐3 Regulates Tight Junction Assembly in Human Retinal Pigment Epithelium
ABSTRACT The retinal pigment epithelium (RPE) consists of polarized epithelial cells, serving as a support system for photoreceptor maintenance, where the polarity is contributed by the distribution of syntaxins (STX) within the cell. STX3, a known regulator of apical trafficking in epithelial cells, was previously understood to be absent in human RPE ...
Athira Ramesh +3 more
wiley +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
Bone marrow mesenchymal stem cells (BMSCs) promote tendon injury repair by enhancing tenocyte function and regulating the FTO/m6A/ELOB axis. Mechanistically, BMSCs lead to the upregulation of FTO and m6A modification, which subsequently suppresses ELOB expression.
Zhao‐Rong Dai +2 more
wiley +1 more source
Purpose: To evaluate the efficacy of intravitreal ranibizumab in eyes with exudative age-related macular degeneration associated with retinal pigment epithelial tear.
Ladas, Ioannis D. +6 more
core +1 more source
To report a case of bullous central serous chorioretinopathy associated with subretinal exudates and a tear of the retinal pigment epithelium imaged using spectral domain optical coherence tomography and treated successfully with reduced fluence ...
Lujan, Brandon J +2 more
core +1 more source
Using micro computed tomography, light microscopy and transmission electron microscopy, this study reveals that the conjunctival portions of the corneal epithelial and spectacular endothelial lining in the eye of the short‐nosed sea snake Aipysurus apraefrontalis possess high densities of microvilli to increase the surface area and two types of ...
H. Barry Collin +4 more
wiley +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
Altered Retinal Dopamine Homeostasis in Murine Models of Retinitis Pigmentosa
Dopamine is an important catecholamine chemical messenger in the light‐sensing retina of the eye, where it serves multiple modulatory functions related to vision. This research studied the changes in the retinal dopamine system in two mouse models (P23H and rd10) of retinitis pigmentosa, which is a disease group of inherited retinal diseases that lead ...
Katri Vainionpää +11 more
wiley +1 more source

